Fingolimod modulates T cell phenotype and regulatory T cell plasticity in vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2018.08.002
Abstract: Fingolimod is an approved therapeutic option for patients with relapsing-remitting multiple sclerosis that primarily functions by sequestering T cells in lymph nodes inhibiting their egress to the central nervous system. However, recent data suggests that… read more here.
Keywords: regulatory cell; fingolimod; multiple sclerosis; modulates cell ... See more keywords
Fingolimod Modulates Dendritic Architecture in a BDNF-Dependent Manner
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21093079
Abstract: The brain-derived neurotrophic factor (BDNF) plays crucial roles in both the developing and mature brain. Moreover, alterations in BDNF levels are correlated with the cognitive impairment observed in several neurological diseases. Among the different therapeutic… read more here.
Keywords: modulates dendritic; bdnf dependent; fingolimod modulates; dendritic architecture ... See more keywords