Prediction of skin permeation and concentration of rhododendrol applied as finite dose from complex cosmetic vehicles.
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DOI: 10.1016/j.ijpharm.2020.119186
Abstract: Finite dose experiments represent clinical use wherein depletion of dose, evaporation of excipients, and gradual change in vehicle composition may occur. In the present study, we attempted a mathematical approach for predicting skin permeation and… read more here.
Keywords: permeation concentration; permeation; finite dose; applied finite ... See more keywords
Usefulness of Artificial Membrane, Strat-M®, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions
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DOI: 10.3390/pharmaceutics12020173
Abstract: The ban on the use of animals in testing cosmetic products has led to the development of animal-free in vitro methods. Strat-M® is an artificial membrane engineered to mimic human skin and is recommended as… read more here.
Keywords: artificial membrane; permeation; complex vehicles; finite dose ... See more keywords
A Mathematical Approach Using Strat-M® to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions
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DOI: 10.3390/pharmaceutics14071370
Abstract: Estimation of the percutaneous absorption is essential for the safety assessment of cosmetic and dermopharmaceutical products. Currently, an artificial membrane, Strat-M®, has been focused on as the tool which could obtain the permeation parameters close… read more here.
Keywords: using strat; percutaneous absorption; finite dose; permeation parameters ... See more keywords