Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion-associated myeloid neoplasm.
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DOI: 10.1182/bloodadvances.2021004966
Abstract: FIP1L1-RARA associated neoplasm is a very rare and aggressive disease, with only 3 previously reported cases in the literature. Herein we describe a 9-month-old boy who presented with a FIP1L1-RARA fusion associated myelodysplastic/myeloproliferative (MDS/MPN) neoplasm-like… read more here.
Keywords: rara fusion; fip1l1 rara; rara; fusion associated ... See more keywords
Acute promyelocytic leukemia with FIP1L1::RARA fusion gene: The clinical utility of transcriptome sequencing and bioinformatic analyses
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DOI: 10.3389/fonc.2022.1049473
Abstract: Background Acute promyelocytic leukemia (APL) is typically characterized by the presence of coagulopathy and the PML::RARA fusion gene. The FIP1L1::RARA has been reported as a novel fusion gene, but studies on its pathogenesis are limited.… read more here.
Keywords: rara; fip1l1 rara; rara fusion; signaling pathway ... See more keywords