Articles with "firing" as a keyword



Sleep, synaptic homeostasis and neuronal firing rates

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Published in 2017 at "Current Opinion in Neurobiology"

DOI: 10.1016/j.conb.2017.03.016

Abstract: The synaptic homeostasis hypothesis (SHY) states that wake brings about a net overall increase in synaptic strength in many brain circuits that needs to be renormalized by sleep. I will review recent studies that were… read more here.

Keywords: firing rates; synaptic homeostasis; neuronal firing; firing ... See more keywords

Entrainment of Circadian Rhythms Depends on Firing Rates and Neuropeptide Release of VIP SCN Neurons

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Published in 2018 at "Neuron"

DOI: 10.1016/j.neuron.2018.06.029

Abstract: The mammalian suprachiasmatic nucleus (SCN) functions as a master circadian pacemaker, integrating environmental input to align physiological and behavioral rhythms to local time cues. Approximately 10% of SCN neurons express vasoactive intestinal polypeptide (VIP); however,… read more here.

Keywords: release vip; circadian rhythms; firing; scn neurons ... See more keywords

Characterization of Superficial Dorsal Horn Neurons from “Tamamaki” Mice and Stability of their GAD67-EGFP Phenotype in Defined-Medium Organotypic Culture

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Published in 2018 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2017.12.047

Abstract: Defined medium organotypic cultures (DMOTC) containing spinal dorsal horn neurons are especially useful in studying the etiology and pharmacology of chronic pain. We made whole-cell recordings from neurons in acutely isolated mouse spinal cord slices… read more here.

Keywords: gad67 egfp; gad67; firing; egfp phenotype ... See more keywords
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Optimized Model Selection for Concurrent Decoding of Finger Kinetics and Kinematics

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Published in 2023 at "IEEE Access"

DOI: 10.1109/access.2023.3246950

Abstract: Myoelectric-based motor intent detection is typically used to interface with assistive devices. However, the intent detection performance is sensitive to interference of electromyogram (EMG) signals. Recently, EMG signals are decomposed into motor units (MU) firing… read more here.

Keywords: kinematics; firing frequency; motor; model ... See more keywords

Fluctuation Scaling of Neuronal Firing and Bursting in Spontaneously Active Brain Circuits

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Published in 2020 at "International journal of neural systems"

DOI: 10.1142/s0129065719500175

Abstract: We employed high-density microelectrode arrays to investigate spontaneous firing patterns of neurons in brain circuits of the primary somatosensory cortex (S1) in mice. We recorded from over 150 neurons for 10min in each of eight… read more here.

Keywords: brain circuits; firing bursting; firing; power ... See more keywords

Persistent inflammation selectively activates opioid-sensitive phasic-firing neurons within the vlPAG.

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Published in 2023 at "Journal of neurophysiology"

DOI: 10.1152/jn.00016.2023

Abstract: The ventrolateral periaqueductal gray (vlPAG) is a key brain area within the descending pain modulatory pathway and an important target for opioid-induced analgesia. The vlPAG contains heterogeneous neurons with respect to neurotransmitter content, receptor and… read more here.

Keywords: inflammation; inflammation selectively; opioid sensitive; vlpag ... See more keywords

Distinct firing responses to synthetic synaptic currents in the adult murine reticular and relay thalamus

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Published in 2025 at "Journal of neurophysiology"

DOI: 10.1152/jn.00052.2025

Abstract: Numerous cortical and subcortical inputs innervate the thalamus and robustly control thalamic activity. These synaptic inputs differ in shape and undergo dynamic changes throughout development and disease conditions. How the shape of postsynaptic currents regulates… read more here.

Keywords: nrt neurons; relay; synaptic currents; thalamus ... See more keywords

Sympathetic Action Potential Firing and Recruitment Patterns Are Abnormal in Gestational Hypertension

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Published in 2022 at "Hypertension"

DOI: 10.1161/hypertensionaha.122.19754

Abstract: Background: We tested the hypothesis that women who develop gestational hypertension (GH) display abnormal sympathetic action potential (AP) discharge patterns during late pregnancy (32–36 weeks), both at supine rest and during postural stress. Methods: Thirteen… read more here.

Keywords: spikes burst; action potential; gestational hypertension; sympathetic action ... See more keywords

Selective modulation of neuronal firing by pulse stimulations with different frequencies in rat hippocampus

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Published in 2019 at "BioMedical Engineering OnLine"

DOI: 10.1186/s12938-019-0700-z

Abstract: BackgroundDeep brain stimulation (DBS) has a good prospect for treating many brain diseases. Recent studies have shown that axonal activation induced by pulse stimulations may play an important role in DBS therapies through wide projections… read more here.

Keywords: stimulations different; frequency; stimulation; firing ... See more keywords

Electrical coupling controls dimensionality and chaotic firing of inferior olive neurons

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Published in 2020 at "PLoS Computational Biology"

DOI: 10.1371/journal.pcbi.1008075

Abstract: We previously proposed, on theoretical grounds, that the cerebellum must regulate the dimensionality of its neuronal activity during motor learning and control to cope with the low firing frequency of inferior olive neurons, which form… read more here.

Keywords: electrical coupling; firing; dimensionality; inferior olive ... See more keywords

Assessing NaV1.7 during tonic firing in pig C-nociceptors

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Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0335081

Abstract: Assuming the voltage-gated sodium channel (VGSC) NaV1.7 facilitates action potential generation upon slow electrical depolarization, we investigated protoxin II and TTX to target VGSC sub-types and to assess their role in C-fiber excitability when stimulated… read more here.

Keywords: assessing nav1; action; action potential; nav1 tonic ... See more keywords