Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase
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DOI: 10.1038/s41467-021-21165-9
Abstract: Aspartate transcarbamoylase (ATC), an essential enzyme for de novo pyrimidine biosynthesis, is uniquely regulated in plants by feedback inhibition of uridine 5-monophosphate (UMP). Despite its importance in plant growth, the structure of this UMP-controlled ATC… read more here.
Keywords: active sites; firing active; plant; aspartate transcarbamoylase ... See more keywords