Clustering of Neuropsychiatric Disease in First-Degree and Second-Degree Relatives of Patients With Amyotrophic Lateral Sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.2699
Abstract: Importance Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative condition primarily involving the motor system. There is increasing epidemiologic evidence of an association between ALS and a wider spectrum of neurodegenerative and neuropsychiatric disorders among… read more here.
Keywords: degree relatives; first degree; second degree; relatives patients ... See more keywords
Risk of Syndrome-Associated Cancers Among First-Degree Relatives of Patients With Pancreatic Ductal Adenocarcinoma With Pathogenic or Likely Pathogenic Germline Variants.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2023.0806
Abstract: Importance Increased cancer risk in first-degree relatives of probands with pancreatic ductal adenocarcinoma (PDAC probands) who carry pathogenic or likely pathogenic germline variants (PGVs) in cancer syndrome-associated genes encourages cascade genetic testing. To date, unbiased… read more here.
Keywords: pdac probands; syndrome associated; degree relatives; first degree ... See more keywords
High prevalence of diabetes‐specific autoimmunity in first‐degree relatives of Sardinian patients with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.2864
Abstract: The incidence of type 1 diabetes mellitus (T1DM) in Sardinia is among the highest in the world (44.8 cases/100,000 person‐years). Recommendations of the Immunology of Diabetes Society advise evaluating autoantibody positivity in first‐degree relatives (FDRs)… read more here.
Keywords: degree relatives; first degree; high prevalence; type diabetes ... See more keywords
Familial implications of autoimmune disease: Recurrence risks of alopecia areata and associated conditions in first‐degree relatives
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Genetic Counseling"
DOI: 10.1002/jgc4.1178
Abstract: Alopecia areata (AA), a complex autoimmune hair loss condition, affects approximately 2.1% of the population. Individuals with AA have increased susceptibility to diseases such as atopy and autoimmune disorders, but little is known about first‐degree… read more here.
Keywords: degree relatives; alopecia areata; associated conditions; first degree ... See more keywords
Association between PR Interval, First‐degree atrioventricular block and major arrhythmic events in patients with Brugada syndrome – Systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12188
Abstract: Risk stratification in patients with asymptomatic Brugada Syndrome is challenging, and despite recent advances, there is no clear evidence. The first‐degree atrioventricular block was hypothesized to be a predictor of arrhythmic events. Measurement of the… read more here.
Keywords: first degree; block; atrioventricular block; brugada syndrome ... See more keywords
Fatalism and metaphor in Confucianism: A qualitative study of barriers to genetic testing among first‐degree relatives of hereditary cancer patients from China
Sign Up to like & getrecommendations! Published in 2022 at "Psycho-Oncology"
DOI: 10.1002/pon.6068
Abstract: Despite the benefits, the rate of genetic testing among first‐degree relatives (FDRs; parents, children, and siblings) remains low, and the barriers to undergoing testing among FDRs in China are not clear. We explored the reasons… read more here.
Keywords: degree relatives; genetic testing; first degree; testing among ... See more keywords
High frequency of rheumatic regional pain syndromes in first-degree relatives of patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05029-z
Abstract: First-degree relatives (FDR) of patients with rheumatoid arthritis (RA) have a higher risk for the development of RA. In the stages prior to the development of arthritis, nonspecific musculoskeletal (MSK) manifestations may occur. The aim… read more here.
Keywords: degree relatives; first degree; pain; rheumatoid arthritis ... See more keywords
[Family history of first degree as a risk factor for colorectal cancer].
Sign Up to like & getrecommendations! Published in 2021 at "Gaceta sanitaria"
DOI: 10.1016/j.gaceta.2021.04.006
Abstract: OBJECTIVE To evaluate the association between first-degree family history and colorectal cancer (CRC). METHOD We analyzed data from 2857 controls and 1360 CRC cases, collected in the MCC-Spain project. The adjusted odds ratio (OR) and… read more here.
Keywords: family history; colorectal cancer; first degree;
Outcomes of screening gastroscopy in first-degree relatives of patients fulfilling hereditary diffuse gastric cancer criteria.
Sign Up to like & getrecommendations! Published in 2018 at "Gastrointestinal endoscopy"
DOI: 10.1016/j.gie.2017.04.016
Abstract: BACKGROUND AND AIMS The aim of this study was to determine the yield of endoscopic screening in first-degree relatives (FDRs) of CDH1-negative hereditary diffuse-type gastric cancer (HDGC) patients. METHODS In this retrospective observational cohort study,… read more here.
Keywords: diffuse; degree relatives; first degree; gastric cancer ... See more keywords
Aberrant probabilistic reinforcement learning in first-degree relatives of individuals with bipolar disorder.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2019.11.063
Abstract: BACKGROUND Motivational dysregulation represents a core vulnerability factor for bipolar disorder. Whether this also comprises aberrant learning of stimulus-reinforcer contingencies is less clear. METHODS To answer this question, we compared healthy first-degree relatives of individuals… read more here.
Keywords: degree relatives; first degree; disorder; reinforcement learning ... See more keywords
A study of oxidative stress biomarkers in obsessive compulsive disorder
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Obsessive-Compulsive and Related Disorders"
DOI: 10.1016/j.jocrd.2017.09.004
Abstract: Abstract Background Existing literature supports the potential role of oxidative stress in pathogenesis of psychiatric disorders like schizophrenia, depression, anxiety disorders, substance use disorders and neurodevelopmental disorders. Role of oxidative stress has also been implicated… read more here.
Keywords: first degree; compulsive disorder; obsessive compulsive; study ... See more keywords