Fabrication of monolithic frits and columns for chip-based multidimensional separation devices.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202100901
Abstract: In this work, devices for two-dimensional separations are considered. The device contains a flow distributor, a first-dimension channel, and 17 second-dimension outlets. In the design, all connections between the first-dimension channel, the flow distributor, and… read more here.
Keywords: monolithic frits; fabrication monolithic; dimension channel; first dimension ... See more keywords
LCxSFC Valve Technologies: Guidelines toward a Successful Online Modulation.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c03263
Abstract: Online two-dimensional liquid chromatography can be used under various separation modes but is sometimes limited in terms of orthogonality, especially for the analysis of neutral compounds. The use of SFC in the second dimension offers… read more here.
Keywords: dimension; valve; first dimension; second dimension ... See more keywords
Separation orthogonality in liquid chromatography-mass spectrometry for proteomic applications: comparison of 16 different two-dimensional combinations.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b05407
Abstract: Peptide separation orthogonality for 16 different 2D LC-ESI MS systems has been evaluated. To compare and contrast the behavior of the first dimension columns, a large proteomic retention dataset of ~30,000 tryptic peptides was collected… read more here.
Keywords: separation; first dimension; liquid chromatography; separation orthogonality ... See more keywords