Assessment of Insulin Resistance Among Drug-Naive Patients With First-Episode Schizophrenia in the Context of Hormonal Stress Axis Activation
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2017.1983
Abstract: Before the introduction of antipsychotics, links between schizophrenia and abnormal glucose metabolism levels were found in the late 1800s as an increased prevalence of diabetes in families with a history of “insanity.”1 Furthermore, it is… read more here.
Keywords: among drug; schizophrenia; first episode; insulin resistance ... See more keywords
Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2018.3637
Abstract: Importance The use of high-field magnetic resonance spectroscopy (MRS) in multiple brain regions of a large population of human participants facilitates in vivo study of localized or diffusely altered brain metabolites in patients with first-episode… read more here.
Keywords: resonance spectroscopy; magnetic resonance; first episode; patients first ... See more keywords
Psychotic symptoms in first-episode and drug naïve patients with major depressive disorder: Prevalence and related clinical factors.
Sign Up to like & getrecommendations! Published in 2020 at "Depression and anxiety"
DOI: 10.1002/da.23026
Abstract: BACKGROUND Many patients with major depressive disorder (MDD) have been found to have psychotic symptoms. However, few studies have reported the prevalence of comorbid psychotic symptoms in first-episode drug naïve (FEDN) MDD patients. This study… read more here.
Keywords: mdd patients; anxiety; first episode; prevalence ... See more keywords
Parahippocampal area three gray matter is reduced in first‐episode schizophrenia spectrum: Discovery and replication samples
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25256
Abstract: Early course schizophrenia is associated with reduced gray matter. The specific structures affected first and how deficits impact symptoms and cognition remain unresolved. We used the Human Connectome Project multimodal parcellation (HCP‐MMP) to precisely identify… read more here.
Keywords: replication samples; schizophrenia; discovery replication; gray matter ... See more keywords
Multimodal MRI assessment for first episode psychosis: A major change in the thalamus and an efficient stratification of a subgroup
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25276
Abstract: Multi‐institutional brain imaging studies have emerged to resolve conflicting results among individual studies. However, adjusting multiple variables at the technical and cohort levels is challenging. Therefore, it is important to explore approaches that provide meaningful… read more here.
Keywords: first episode; multimodal mri; assessment first; mri assessment ... See more keywords
Morphological fingerprinting: Identifying patients with first‐episode schizophrenia using auto‐encoded morphological patterns
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.26098
Abstract: Although a large number of case–control statistical and machine learning studies have been conducted to investigate structural brain changes in schizophrenia, how best to measure and characterize structural abnormalities for use in classification algorithms remains… read more here.
Keywords: encoded morphological; episode schizophrenia; first episode; auto encoded ... See more keywords
Heterogeneous brain dynamic functional connectivity patterns in first‐episode drug‐naive patients with major depressive disorder
Sign Up to like & getrecommendations! Published in 2023 at "Human Brain Mapping"
DOI: 10.1002/hbm.26266
Abstract: It remains challenging to identify depression accurately due to its biological heterogeneity. As people suffering from depression are associated with functional brain network alterations, we investigated subtypes of patients with first‐episode drug‐naive (FEDN) depression based… read more here.
Keywords: connectivity; network; first episode; episode drug ... See more keywords
Altered hippocampal centrality and dynamic anatomical covariance of intracortical microstructure in first episode psychosis
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DOI: 10.1002/hipo.23215
Abstract: Hippocampal circuitry has been posited to be fundamental to positive symptoms in psychosis, but its contributions to other factors important for outcome remains unclear. We hypothesized that longitudinal changes in the hippocampal circuit and concomitant… read more here.
Keywords: first episode; dynamic anatomical; intracortical microstructure; episode psychosis ... See more keywords
Abnormal dynamic functional connectivity in first‐episode, drug‐naïve adolescents with major depressive disorder
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25047
Abstract: Previous neuroimaging studies have identified disrupted large‐scale functional brain networks in major depressive disorder (MDD); however, most of them focused on adult patients and were based on static functional connectivity (FC). Thus, we aimed to… read more here.
Keywords: state; first episode; major depressive; functional connectivity ... See more keywords
Clinical course and cost assessment of infants with a first episode of acute bronchiolitis presenting to the emergency department: Data from the GUERANDE clinical trial.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric pulmonology"
DOI: 10.1002/ppul.25621
Abstract: INTRODUCTION Bronchiolitis is the leading cause of hospitalization for infants but its economic burden is not well documented. Our objective was to describe the clinical evolution and to assess the 1-month cost of a first… read more here.
Keywords: bronchiolitis; episode acute; acute bronchiolitis; first episode ... See more keywords
The role of expectations in mental disorders and their treatment
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DOI: 10.1002/wps.20427
Abstract: patients were scanned after they had been treated with antipsychotic medication: it is thus unclear whether the neuroimaging findings predated treatment or were secondary to it. Most studies to date have related clinical outcomes to… read more here.
Keywords: ongoing studies; clinical outcomes; treatment; first episode ... See more keywords