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Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.01.021
Abstract: Abstract For the very first time furo[3,2-c]pyrazoles have been prepared starting from pyrazole building blocks instead from furanes. During this synthesis effort two previously unknown heterocyclic scaffolds have been discovered, the furo[3,2-c]pyrazol-6-ones and the 2-cyano-3-aminofuran-4-ones.
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Keywords:
synthesis derivatization;
pyrazol ones;
furo pyrazol;
first synthesis ... See more keywords
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Published in 2023 at "CrystEngComm"
DOI: 10.1039/d3ce00163f
Abstract: A new polymorph of hydroxyurea (HU) was crystallized 150 years after its first synthesis. Due to its medicinal use in neoplastic diseases and sickle cell anemia, a high throughput screen...
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Keywords:
polymorph hydroxyurea;
first synthesis;
years first;
150 years ... See more keywords
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Published in 2020 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2019.1680643
Abstract: Abstract Herein, we report a concise and efficient method for the synthesis of p-hydroxyphenyl caffeate, a novel natural caffeic acid ester derivative isolated from Wedelia trilobata. The key feature of this synthesis is the Verley–Doebner…
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Keywords:
immunomodulatory properties;
synthesis immunomodulatory;
caffeate;
first synthesis ... See more keywords
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Published in 2019 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989019011393
Abstract: A modified synthesis procedure allowed lapachol acetate (acetic acid 3-(3-methyl-but-2-enyl)-1,4-dioxo-1,4-dihydro- naphthalen-2-yl ester) to be obtained in high yield and its crystal structure is reported for the first time 80 years after its first synthesis. The…
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Keywords:
first synthesis;
crystal structure;
lapachol acetate;
years first ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043550
Abstract: The emergence of drug-resistant bacteria and fungi represents a serious health problem worldwide. It has long been known that cationic compounds can inhibit the growth of bacteria and fungi by disrupting the cell membrane. The…
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Keywords:
first synthesis;
dbu;
synthesis;
bacteria fungi ... See more keywords