LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "fis1" as a keyword



Photo from wikipedia

The mitochondrial fission factor FIS1 promotes stemness of human lung cancer stem cells via mitophagy

Sign Up to like & get
recommendations! Published in 2021 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13207

Abstract: Mitophagy, a form of autophagy, plays a role in cancer development, progression and recurrence. Cancer stem cells (CSCs) also play a key role in these processes, although it not known whether mitophagy can regulate the… read more here.

Keywords: cancer stem; mitochondrial fission; cancer; fis1 ... See more keywords
Photo by kommumikation from unsplash

Iron chelation promotes mitophagy through SENP3-mediated deSUMOylation of FIS1

Sign Up to like & get
recommendations! Published in 2022 at "Autophagy"

DOI: 10.1080/15548627.2022.2046898

Abstract: ABSTRACT The selective clearance of mitochondria by mitophagy is an important quality control mechanism for maintaining mitochondrial and cellular health. Iron chelation, for example by the compound deferiprone (DFP), leads to a specific form of… read more here.

Keywords: senp3; fis1; dfp; iron chelation ... See more keywords
Photo by kellysikkema from unsplash

Hepatic Fis1 regulates mitochondrial integrated stress response and improves metabolic homeostasis

Sign Up to like & get
recommendations! Published in 2022 at "JCI Insight"

DOI: 10.1172/jci.insight.150041

Abstract: Mitophagy and mitochondrial integrated stress response (ISR) are 2 primary protective mechanisms to maintain functional mitochondria. Whether these 2 processes are coordinately regulated remains unclear. Here we show that mitochondrial fission 1 protein (Fis1), which… read more here.

Keywords: fis1; stress response; mitochondrial integrated; integrated stress ... See more keywords
Photo by marcinjozwiak from unsplash

Prognostic Significance of the Fission1/Parkin Ratio for Sepsis: A Prospective Cohort Study

Sign Up to like & get
recommendations! Published in 2021 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2021.642749

Abstract: Introduction: Fission1 (Fis1) and parkin are key proteins related to mitochondrial fission and mitophagy, respectively. This study aimed to assess the prognostic value of the Fis1/parkin ratio as a biomarker in patients with sepsis. Methods:… read more here.

Keywords: parkin ratio; fis1; fis1 parkin; patients sepsis ... See more keywords