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Right Ventricular Maladaptation to Pressure Overload in Fischer Rats Is Associated With Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics

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Published in 2022 at "Hypertension"

DOI: 10.1161/hypertensionaha.122.19300

Abstract: Background: We explored the mechanism of maladaptive right ventricular (RV) remodeling in Fischer compared with Sprague-Dawley (SD) rats exposed to pressure overload. Methods: Pulmonary hypertension was induced by injection of the VEGFR antagonist, SU5416, followed… read more here.

Keywords: pressure overload; adenylate kinase; right ventricular; fischer rats ... See more keywords