Strategies to Optimize Anti-tumor Necrosis Factor Therapy for Perianal Fistulizing Crohn’s Disease: A Systematic Review
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DOI: 10.1007/s10620-019-05635-1
Abstract: Tumor necrosis factor (TNF) antagonists are considered the cornerstone therapy for fistulizing perianal Crohn’s disease (PCD), yet a substantial proportion of patients fail to achieve healing. Therefore, we reviewed the evidence for strategies to enhance… read more here.
Keywords: tnf; fistula healing; anti tnf; tumor necrosis ... See more keywords
Predictors of Perianal Fistula Healing in Children With Newly Diagnosed Crohn Disease
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DOI: 10.1097/mpg.0000000000003595
Abstract: Objectives: Perianal fistulas are among the most severe complications of Crohn disease, but limited data regarding their outcomes are available in children. Our objective was to determine predictors of perianal fistula healing among pediatric patients… read more here.
Keywords: perianal fistula; disease; crohn disease; fistula healing ... See more keywords
Higher infliximab and adalimumab trough levels are associated with fistula healing in patients with fistulising perianal Crohn’s disease
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DOI: 10.3748/wjg.v28.i23.2597
Abstract: BACKGROUND Tumor necrosis factor-alpha inhibitors, including infliximab and adalimumab, are effective medical treatments for perianal fistulising Crohn’s disease (CD), but not all patients achieve fistula healing. AIM To determine the correlation between perianal fistula healing… read more here.
Keywords: adalimumab trough; trough levels; infliximab adalimumab; fistula healing ... See more keywords