Analytical and functional aspects of protein-ligand interactions: Beyond induced fit and conformational selection.
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DOI: 10.1016/j.abb.2021.109064
Abstract: Ligand-dependent changes in protein conformation are foundational to biology. Historical mechanistic models for substrate-specific proteins are induced fit (IF) and conformational selection (CS), which invoke a change in protein conformation after ligand binds or before… read more here.
Keywords: protein; conformational selection; analytical functional; induced fit ... See more keywords