The role of mitosis in generating fitness heterogeneity.
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DOI: 10.1242/jcs.260103
Abstract: Cancer cells have heterogeneous fitness, and this heterogeneity stems from genetic and epigenetic sources. Here, we sought to assess the contribution of asymmetric mitosis (AM) and time on the variability of fitness in sister cells.… read more here.
Keywords: fitness heterogeneity; mitosis; erk activity;