LAUSR

Fixation probability of a nonmutator in a large population of asexual mutators.

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0 Published in 2017 at "Journal of theoretical biology"

DOI: 10.1016/j.jtbi.2017.08.027

Abstract: In an adapted population of mutators in which most mutations are deleterious, a nonmutator that lowers the mutation rate is under indirect selection and can sweep to fixation. Using a multitype branching process, we calculate… read more here.

Keywords: nonmutator large; fixation probability; population; nonmutator ... See more keywords

The fixation probability and time for a doubly beneficial mutant

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1 Published in 2018 at "Stochastic Processes and their Applications"

DOI: 10.1016/j.spa.2018.01.004

Abstract: For a highly beneficial mutant $A$ entering a randomly reproducing population of constant size, we study the situation when a second beneficial mutant $B$ arises before $A$ has fixed. If the selection coefficient of $B$… read more here.

Keywords: fixation probability; beneficial mutant; time;

Amplification on Undirected Population Structures: Comets Beat Stars

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0 Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-00107-w

Abstract: The fixation probability is the probability that a new mutant introduced in a homogeneous population eventually takes over the entire population. The fixation probability is a fundamental quantity of natural selection, and known to depend… read more here.

Keywords: probability; fixation probability; population structures; undirected graphs ... See more keywords

Population structure determines the tradeoff between fixation probability and fixation time

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0 Published in 2019 at "Communications Biology"

DOI: 10.1038/s42003-019-0373-y

Abstract: The rate of biological evolution depends on the fixation probability and on the fixation time of new mutants. Intensive research has focused on identifying population structures that augment the fixation probability of advantageous mutants. But… read more here.

Keywords: fixation probability; fixation time; population; fixation ... See more keywords

The network structure affects the fixation probability when it couples to the birth-death dynamics in finite population

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1 Published in 2021 at "PLoS Computational Biology"

DOI: 10.1371/journal.pcbi.1009537

Abstract: The study of evolutionary dynamics on graphs is an interesting topic for researchers in various fields of science and mathematics. In systems with finite population, different model dynamics are distinguished by their effects on two… read more here.

Keywords: network structure; fixation probability; probability; finite population ... See more keywords