FAP20 is required for flagellum assembly in Trypanosoma brucei
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e23-12-0497
Abstract: Trypanosoma brucei is a human and animal pathogen that depends on flagellar motility for transmission and infection. The trypanosome flagellum is built around a canonical “9+2” axoneme, containing nine doublet microtubules (DMTs) surrounding two singlet… read more here.
Keywords: flagellum assembly; fap20; flagellum; trypanosoma brucei ... See more keywords
Trypanosome doublet microtubule structures reveal flagellum assembly and motility mechanisms.
Sign Up to like & getrecommendations! Published in 2025 at "Science"
DOI: 10.1126/science.adr3314
Abstract: The flagellum of Trypanosoma brucei drives the parasite's characteristic screw-like motion and is essential for its replication, transmission, and pathogenesis. However, the molecular details of this process remain unclear. Here, we present high-resolution (up to… read more here.
Keywords: flagellum assembly; motility; assembly motility; trypanosome doublet ... See more keywords