Radiogenomic association between the T2-FLAIR mismatch sign and IDH mutation status in adult patients with lower-grade gliomas: an updated systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Radiology"
DOI: 10.1007/s00330-022-08607-8
Abstract: To reveal a radiogenomic correlation between the presence of the T2-fluid-attenuated inversion recovery resection (T2-FLAIR) mismatch sign on MR images and isocitrate dehydrogenase (IDH) mutation status in adult patients with lower-grade gliomas (LGGs). A web-based… read more here.
Keywords: mismatch sign; sign; flair mismatch; idh mutation ... See more keywords
Deep learning-based quantification of T2-FLAIR mismatch sign: extending IDH mutation prediction in adult-type diffuse lower-grade glioma
Sign Up to like & getrecommendations! Published in 2025 at "European Radiology"
DOI: 10.1007/s00330-025-11475-7
Abstract: To investigate the predictive value of the quantitative T2-FLAIR mismatch ratio (qT2FM) with fully automated tumor segmentation in adult-type diffuse lower-grade gliomas (LGGs). This retrospective study included 218 consecutive patients (mean age, 47 years ± 15 [SD];… read more here.
Keywords: adult type; flair mismatch; idh mutation; mutation ... See more keywords
'Real world' use of a highly reliable imaging sign: 'T2-FLAIR mismatch' for identification of IDH mutant astrocytomas.
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa041
Abstract: The T2-FLAIR mismatch sign is an easily detectable imaging sign on routine clinical MRI studies that suggests diagnosis of IDH-mutant 1p/19q non-codeleted gliomas. Multiple independent studies show that the T2-FLAIR mismatch sign has near-perfect specificity,… read more here.
Keywords: flair mismatch; idh mutant; sign; imaging sign ... See more keywords
Unknown‐onset strokes with anterior circulation occlusion treated by thrombectomy after DWI‐FLAIR mismatch selection
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Neurology"
DOI: 10.1111/ene.13580
Abstract: The DAWN trial recently showed compelling evidence in treating late window and wake‐up stroke patients with thrombectomy using a clinical‐imaging mismatch. The aim was to evaluate the results of thrombectomy for unknown‐onset strokes (UOS) treated… read more here.
Keywords: flair mismatch; dwi flair; onset strokes; unknown onset ... See more keywords
The T2-FLAIR mismatch sign as an imaging biomarker for oligodendrogliomas in dogs.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of veterinary internal medicine"
DOI: 10.1111/jvim.16749
Abstract: BACKGROUND In humans, the T2-weighted (T2W)-fluid-attenuated inversion recovery (FLAIR) mismatch sign (T2FMM) is a specific imaging biomarker for the isocitrate dehydrogenase 1 (IDH1)-mutated, 1p/19q non-codeleted low-grade astrocytomas (LGA). The T2FMM is characterized by a homogeneous… read more here.
Keywords: flair mismatch; biomarker; t2fmm; mismatch sign ... See more keywords
T2–FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower-grade Gliomas: A TCGA/TCIA Project
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-17-0560
Abstract: Purpose: Lower-grade gliomas (WHO grade II/III) have been classified into clinically relevant molecular subtypes based on IDH and 1p/19q mutation status. The purpose was to investigate whether T2/FLAIR MRI features could distinguish between lower-grade glioma… read more here.
Keywords: flair mismatch; mismatch sign; lower grade; flair ... See more keywords
T2-FLAIR mismatch in isocitrate dehydrogenase mutant astrocytomas
Sign Up to like & getrecommendations! Published in 2020 at "Neurology"
DOI: 10.1212/wnl.0000000000010324
Abstract: Objective To assess the predictive value of T2 appearance as a defining criterion of T2–fluid-attenuated inversion recovery (FLAIR) mismatch sign (T2FM), further characterize tumors that display the marker, and describe its radiographic evolution. Methods Records… read more here.
Keywords: flair rim; astrocytomas; flair; flair mismatch ... See more keywords
Use of DWI-FLAIR Mismatch to Estimate the Onset Time in Wake-Up Strokes
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DOI: 10.2147/ndt.s351943
Abstract: Purpose To compare the MRI characteristics of patients with wake-up ischemic stroke (WUS) and with ischemic stroke with known onset time (clear-onset-time stroke, COS) to clarify the role of diffusion-weighted imaging–fluid-attenuated inversion recovery (DWI-FLAIR) mismatch… read more here.
Keywords: flair mismatch; flair; dwi flair; onset time ... See more keywords
Automated Assessment of the DWI-FLAIR Mismatch in Patients with Acute Ischemic Stroke: Added Value to Routine Clinical Practice
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a8170
Abstract: BACKGROUND AND PURPOSE: The DWI-FLAIR mismatch is used to determine thrombolytic eligibility in patients with acute ischemic stroke when the time since stroke onset is unknown. Commercial software packages have been developed for automated DWI-FLAIR… read more here.
Keywords: flair mismatch; dwi flair; stroke;
Adoption of the T2-FLAIR Mismatch Sign among Radiologists: How Well Are We Doing?
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a8783
Abstract: BACKGROUND AND PURPOSE: The classic T2-FLAIR mismatch sign is a highly specific MRI feature that can aid in preoperative diagnosis of isocitrate dehydrogenase (IDH)-mutant 1p/19q noncodeleted gliomas and affect surgical planning. This study aimed to… read more here.
Keywords: idh mutant; flair mismatch; mismatch sign;
CDC42 Might Be a Molecular Signature of DWI-FLAIR Mismatch in a Nonhuman Primate Stroke Model
Sign Up to like & getrecommendations! Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13020287
Abstract: No definitive blood markers of DWI-FLAIR mismatch, a pivotal indicator of salvageable ischemic penumbra brain tissue, are known. We previously reported that CDC42 and RHOA are associated with the ischemic penumbra. Here, we investigated whether… read more here.
Keywords: flair mismatch; dwi flair; flair; cdc42 ... See more keywords