Planarians to schistosomes: an overview of flatworm cell-types and regulators
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Helminthology"
DOI: 10.1017/s0022149x22000621
Abstract: Abstract Schistosomiasis remains a major neglected tropical disease that afflicts over 200 million people globally. Schistosomes, the aetiological agent of schistosomiasis, are parasitic flatworms that propagate between molluscan and mammalian hosts. Inside the mammalian host,… read more here.
Keywords: cell; cell types; schistosomes overview; flatworm ... See more keywords
Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2217732120
Abstract: The drug praziquantel (PZQ) is the key clinical therapy for treating schistosomiasis and other infections caused by parasitic flatworms. A schistosome target for PZQ was recently identified- a transient receptor potential ion channel in the… read more here.
Keywords: parasitic flatworm; sensitivity; pzq; flatworm ... See more keywords
Genome Assembly of the Polyclad Flatworm Prostheceraeus crozieri
Sign Up to like & getrecommendations! Published in 2022 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evac133
Abstract: Polyclad flatworms are widely thought to be one of the least derived of the flatworm classes and, as such, are well placed to investigate evolutionary and developmental features such as spiral cleavage and larval diversification… read more here.
Keywords: polyclad flatworm; prostheceraeus crozieri; genome; flatworm ... See more keywords
First Detection of Tetrodotoxins in the Cotylean Flatworm Prosthiostomum trilineatum
Sign Up to like & getrecommendations! Published in 2021 at "Marine Drugs"
DOI: 10.3390/md19010040
Abstract: Several polyclad flatworm species are known to contain high levels of tetrodotoxin (TTX), but currently TTX-bearing flatworms seem to be restricted to specific Planocera lineages belonging to the suborder Acotylea. During our ongoing study of… read more here.
Keywords: flatworm prosthiostomum; first detection; detection tetrodotoxins; flatworm ... See more keywords
Toxic Flatworm Egg Plates Serve as a Possible Source of Tetrodotoxin for Pufferfish
Sign Up to like & getrecommendations! Published in 2019 at "Toxins"
DOI: 10.3390/toxins11070402
Abstract: The pufferfish Takifugu niphobles (at present Takifugu alboplumbeus) possesses highly concentrated tetrodotoxin (TTX), an extremely potent neurotoxin that provides effective protection from predators, at least at the larval stages. However, the source of the toxin… read more here.
Keywords: toxic flatworm; tetrodotoxin; egg plates; flatworm ... See more keywords