Novel 1,3,4-oxadiazole sulfonate/carboxylate flavonoid derivatives: Synthesis and biological activity.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7197
Abstract: BACKGROUND With the long-term use of traditional bactericides and antiviral agents, drug resistance has become increasingly prominent, resulting in impaired crop growth and yields. Based on this, the introduction of small molecular active groups into… read more here.
Keywords: novel oxadiazole; sulfonate carboxylate; biological activity; carboxylate flavonoid ... See more keywords
Breadfruit flavonoid derivatives attenuate advanced glycation end products (AGEs)-enhanced colon malignancy in HCT116 cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.01.050
Abstract: Abstract Advanced glycation end products (AGEs)-evoked response is an important event in colon tumorigenesis. The aim of this study was to investigate the effect of flavonoid derivatives isolated from breadfruit Artocarpus communis on AGEs-enhanced colon… read more here.
Keywords: age; enhanced colon; colon malignancy; colon ... See more keywords
Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: a systematic review
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DOI: 10.1039/d1ra03196a
Abstract: This review revealed that among all the natural and synthetic flavonoids, the inhibitory findings suggest that the flavonol moiety can serve as an effective and a lead structural scaffold for the further development of novel… read more here.
Keywords: natural synthetic; synthetic flavonoid; new potential; review ... See more keywords
Therapeutic potential of flavonoid derivatives for certain neglected tropical diseases.
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DOI: 10.2174/1389450123666220309093827
Abstract: BACKGROUND Neglected tropical diseases (NTDs) are infectious diseases that mostly affect people living in tropical and subtropical regions, especially in impoverished areas. Ubiquitously found in plants, flavonoids are a group of compounds which have been… read more here.
Keywords: therapeutic potential; neglected tropical; tropical diseases; potential flavonoid ... See more keywords
Lipophilicity as a Central Component of Drug-Like Properties of Chalchones and Flavonoid Derivatives
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DOI: 10.3390/molecules24081505
Abstract: Lipophilcity is an important physico-chemical parameter that influences membrane transport and binding ability to action. Migration distance following complete elution of compounds was used to calculate different lipophilicity-related parameters. The aim of this study is… read more here.
Keywords: central component; lipophilicity central; flavonoid derivatives; like properties ... See more keywords
New Flavonoid Derivatives from Melodorum fruticosum and Their α-Glucosidase Inhibitory and Cytotoxic Activities
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27134023
Abstract: Three new flavonoid derivatives, melodorones A–C (1–3), together with four known compounds, tectochrysin (4), chrysin (5), onysilin (6), and pinocembrin (7), were isolated from the stem bark of Melodorum fruticosum. Their structures were determined on… read more here.
Keywords: derivatives melodorum; glucosidase; new flavonoid; flavonoid derivatives ... See more keywords