Flecainide-Induced QRS Complex Widening Correlates with Negative Inotropy.
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DOI: 10.1016/j.hrthm.2021.04.007
Abstract: BACKGROUND The negative inotropic effect of Class IC antiarrhythmic drugs limits their use for acute cardioversion of atrial fibrillation (AF). OBJECTIVE In an intact porcine model, we examined effects of pulmonary and intravenous (IV) administration… read more here.
Keywords: qrs complex; min; flecainide; contractility ... See more keywords
Under Recognized Toxicity of Flecainide Overdose.
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DOI: 10.1080/10903127.2025.2589459
Abstract: Flecainide is an antiarrhythmic with several adverse effects, including dysrhythmias and hemodynamic collapse with an overdose fatality rate of 22.5% (1-3). Here we present a case of intentional flecainide ingestion leading to critical illness. Emergency… read more here.
Keywords: flecainide; care; flecainide overdose; patient ... See more keywords
Abstract 4359112: Flecainide Reduces Exercise-Induced Arrhythmic Burden in PKP2-Related Arrhythmogenic Cardiomyopathy
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DOI: 10.1161/circ.152.suppl_3.4359112
Abstract: Background: An increased burden of premature ventricular contractions (PVCs)/non-sustained ventricular tachycardia (NSVT) during the recovery phase of exercise stress testing (EST) appears to be a distinctive feature of PKP2-related arrhythmogenic cardiomyopathy (ACM) associated with an… read more here.
Keywords: pkp2 related; flecainide; recovery; burden ... See more keywords
Is the Debate on the Flecainide Action on the RYR2 in CPVT Closed?
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DOI: 10.1161/circresaha.121.318706
Abstract: The class IC antiarrhythmic agent flecainide, developed in the 70s as a more stable local anesthetic by incorporating of fluorine, is nowadays recommended as one of the first-line rhythm control therapeutic options in patients without… read more here.
Keywords: ryr2 cpvt; ryr2; action; flecainide ... See more keywords
Takotsubo cardiomyopathy and flecainide toxicity: a case report and brief literature review.
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DOI: 10.26355/eurrev_202106_26048
Abstract: OBJECTIVE Takotsubo syndrome, also known as stress cardiomyopathy, is predominantly reported in postmenopausal women and it is often triggered by a physical or emotional stressor. CASE REPORT We present the case of a 44-year-old Caucasian… read more here.
Keywords: case; review; flecainide; takotsubo cardiomyopathy ... See more keywords