Structural flexibility of human α‐dystroglycan
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DOI: 10.1002/2211-5463.12259
Abstract: Dystroglycan (DG), composed of α and β subunits, belongs to the dystrophin‐associated glycoprotein complex. α‐DG is an extracellular matrix protein that undergoes a complex post‐translational glycosylation process. The bifunctional glycosyltransferase like‐acetylglucosaminyltransferase (LARGE) plays a crucial… read more here.
Keywords: flexibility human; murine; flexibility; structural flexibility ... See more keywords
Mechanical Durability and Flexibility in Perovskite Photovoltaics: Advancements and Applications
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DOI: 10.1002/adma.202312041
Abstract: The remarkable progress in perovskite solar cell (PSC) technology has witnessed a remarkable leap in efficiency within the past decade. As this technology continues to mature, flexible PSCs (F‐PSCs) are emerging as pivotal components for… read more here.
Keywords: flexibility perovskite; perovskite photovoltaics; mechanical durability; pscs ... See more keywords
Crystalline Confinement of Dynamic Room-Temperature Phosphorescent Hydrogels: A New Paradigm for Synergistic Enhancement between Lifetime and Flexibility.
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DOI: 10.1002/adma.202514693
Abstract: Dynamic room‐temperature phosphorescence (RTP) materials present promising applications in optoelectronic fields. However, conventional dynamic RTP hydrogels typically suffer from an inherent performance trade‐off, where enhancement of flexibility comes at the expense of phosphorescence lifetime and… read more here.
Keywords: dynamic room; phosphorescence; flexibility; room temperature ... See more keywords
Insights into Siglec‐7 Binding to Gangliosides: NMR Protein Assignment and the Impact of Ligand Flexibility
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DOI: 10.1002/advs.202415782
Abstract: Gangliosides, sialylated glycosphingolipids abundant in the nervous system, play crucial roles in neurotransmission, interaction with regulatory proteins, cell–cell recognition, and signaling. Altered gangliosides expression has been correlated with pathological processes, including cancer, inflammatory disorders, and… read more here.
Keywords: cancer; gangliosides nmr; binding gangliosides; siglec binding ... See more keywords
Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations
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DOI: 10.1002/advs.202416331
Abstract: Derived from the bacterial immune system, CRISPR/Cas9 induces DSBs at specific DNA sequences, which are repaired by the cell's endogenous mechanisms, leading to gene insertions, deletions, or substitutions. Despite its transformative potential, several challenges remain… read more here.
Keywords: crispr cas; specificity; flexibility; accessibility ... See more keywords
Dyadic flexibility mediates the relation between parent conflict and infants’ vagal reactivity during the Face‐to‐Face Still‐Face
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DOI: 10.1002/dev.21508
Abstract: Parent conflict is related to attenuated infant vagal reactivity, suggesting less effective regulation. Because infants' self-regulation develops in the context of coregulation, the current study examined a novel measure, flexibility, purported to reflect dyadic reorganization… read more here.
Keywords: vagal reactivity; face; parent conflict; flexibility ... See more keywords
Patterns and controls of foliar nutrient stoichiometry and flexibility across United States forests.
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DOI: 10.1002/ecy.3909
Abstract: Plant element stoichiometry and stoichiometric flexibility strongly regulate ecosystem responses to global change. Here, we tested three potential mechanistic drivers (climate, soil nutrients, and plant taxonomy) of both using paired foliar and soil nutrient data… read more here.
Keywords: foliar nutrient; controls foliar; chemistry; stoichiometry ... See more keywords
The neurophysiological basis of developmental changes during sequential cognitive flexibility between adolescents and adults
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DOI: 10.1002/hbm.24394
Abstract: Cognitive flexibility is a major facet of executive functions and often refers to sequential task control; that is, it is very likely that one may re‐encounter a task that has previously been abandoned to carry… read more here.
Keywords: backward inhibition; sequential cognitive; neurophysiological basis; flexibility ... See more keywords
A meta‐analysis of cognitive flexibility in aging: Perspective from functional network and lateralization
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DOI: 10.1002/hbm.70031
Abstract: Cognitive flexibility, the ability to switch between mental processes to generate appropriate behavioral responses, is reduced with typical aging. Previous studies have found that age‐related declines in cognitive flexibility are often accompanied by variations in… read more here.
Keywords: lateralization; analysis; cognitive flexibility; activation ... See more keywords
Disrupted Structure–Function Integration in Systemic Lupus Erythematosus and Its Impact on Cognitive Flexibility
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DOI: 10.1002/hbm.70299
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, with cognitive dysfunction being one of its most common neuropsychiatric manifestations. Cognitive flexibility relies on the integration of brain structure and function, with white matter networks… read more here.
Keywords: integration; flexibility; structure function; cognitive flexibility ... See more keywords
Analysis of changes of cavity volumes in predefined directions of protein motions and cavity flexibility
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DOI: 10.1002/jcc.26799
Abstract: Dynamics of protein cavities associated with protein fluctuations and conformational plasticity is essential for their biological function. NMR ensembles, molecular dynamics (MD) simulations, and normal mode analysis (NMA) provide appropriate frameworks to explore functionally relevant… read more here.
Keywords: cavity volumes; analysis changes; changes cavity; flexibility ... See more keywords