Free energy landscape of siRNA-polycation complexation: Elucidating the effect of molecular geometry, polymer flexibility, and charge neutralization
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DOI: 10.1371/journal.pone.0186816
Abstract: The success of medical threatments with DNA and silencing interference RNA is strongly related to the design of efficient delivery technologies. Cationic polymers represent an attractive strategy to serve as nucleic-acid carriers with the envisioned… read more here.
Keywords: molecular geometry; flexibility; geometry; flexibility charge ... See more keywords