In vitro and in vivo activity of ciprofloxacin/fosfomycin combination therapy against ciprofloxacin-resistant Shigella flexneri isolates
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DOI: 10.2147/idr.s208071
Abstract: Objective: Ciprofloxacin resistance (CIPR) for Shigella isolates is becoming more prevalent. This study systematically investigated the antibacterial activity of ciprofloxacin (CIP)/fosfomycin (FOS) combination in vitro and in vivo against CIPR S. flexneri isolates. Method: Eighty… read more here.
Keywords: flexneri isolates; fos combination; combination; activity ... See more keywords
Characterization of Extended-Spectrum β-Lactamase Genes of Shigella flexneri Isolates With Fosfomycin Resistance From Patients in China
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DOI: 10.3343/alm.2017.37.5.415
Abstract: Background The emergence of fosfomycin resistance and extended-spectrum β-lactamase (ESBL) genes is a serious threat to public health and a new challenge in shigellosis treatment. The purpose of this study was to identify fosfomycin resistance… read more here.
Keywords: flexneri isolates; lactamase genes; resistance; fosfomycin resistance ... See more keywords