Effect of Counting Genetic Variants on Precision Treatment for Pediatric Atopic Dermatitis: Do Count Your Chickens Before They Hatch.
Sign Up to like & getrecommendations! Published in 2017 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2016.4468
Abstract: Atopic dermatitis (AD) is a common inflammatory skin disorder, and its prevalence in the pediatric population has tripled in the past several decades alone.1 Atopic dermatitis is characterized by xerotic or scaly patches of skin… read more here.
Keywords: flg lof; medicine; dermatology; treatment ... See more keywords
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort
Sign Up to like & getrecommendations! Published in 2024 at "JCI Insight"
DOI: 10.1172/jci.insight.178258
Abstract: Loss-of-function (LoF) variants in the filaggrin (FLG) gene are the strongest known genetic risk factor for atopic dermatitis (AD), but the impact of these variants on AD outcomes is poorly understood. We comprehensively identified genetic… read more here.
Keywords: lof; flg lof; variants associated; atopic dermatitis ... See more keywords