Articles with "fli1 variants" as a keyword



FLI1 and GATA1 govern TLN1 transcription: new insights into FLI1-related platelet disorders

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Published in 2025 at "Haematologica"

DOI: 10.3324/haematol.2024.286372

Abstract: Germline variants of FLI1, essential for megakaryopoiesis, are linked to bleeding disorders, platelet aggregation defects and mild thrombocytopenia. However, the mechanisms behind these abnormalities remain unclear. This study aims to elucidate the impact of FLI1… read more here.

Keywords: platelet; fli1; patients platelets; fli1 variants ... See more keywords