Design, preparation, and in vitro evaluation of gastroretentive floating matrix tablet of mitiglinide
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1140351
Abstract: The present research is focused on developing floating matrix tablets of mitiglinide to prolong its gastric residence time for better absorption. Gastroretentive tablets were prepared using a direct compression technique with hydroxypropyl methylcellulose K15M (HPMC… read more here.
Keywords: time; floating matrix; matrix tablet; drug release ... See more keywords
Design and Evaluation of Losartan Potassium Effervescent Floating Matrix Tablets: In Vivo X-ray Imaging and Pharmacokinetic Studies in Albino Rabbits
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DOI: 10.3390/polym13203476
Abstract: Losartan potassium (LP) is an angiotensin receptor blocker used to treat hypertension. At higher pH, it shows poor aqueous solubility, which leads to poor bioavailability and lowers its therapeutic effectiveness. The main aim of this… read more here.
Keywords: losartan potassium; effervescent floating; ray imaging; effervescent ... See more keywords