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   Articles with "flotillin" as a keyword



Flotillins in the intercalated disc are potential modulators of cardiac excitability.

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recommendations! Published in 2019 at "Journal of molecular and cellular cardiology"

DOI: 10.1016/j.yjmcc.2018.11.007

Abstract: BACKGROUND The intercalated disc (ID) is important for cardiac remodeling and has become a subject of intensive research efforts. However, as yet the composition of the ID has still not been conclusively resolved and the… read more here.

Keywords: flotillin flotillin; flotillin; flotillins intercalated; intercalated disc ... See more keywords

INVESTIGATING THE ROLE OF FLOTILLIN-1 AND HIGH MOBILITY GROUP BOX 1 IN HISTONE 3 MUTATED PAEDIATRIC HIGH-GRADE GLIOMAS

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf185.048

Abstract: Paediatric gliomas are the most prevalent central nervous system tumours diagnosed between birth and age 19. Gain-of-function mutation in H3 histone tail can contribute to a subset of paediatric high-grade gliomas (pHGGs). Our previous research… read more here.

Keywords: paediatric high; flotillin; cell; expression ... See more keywords

Flotillin-mediated endocytosis and ALIX–syntenin-1–mediated exocytosis protect the cell membrane from damage caused by necroptosis

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recommendations! Published in 2019 at "Science Signaling"

DOI: 10.1126/scisignal.aaw3423

Abstract: Two independent trafficking pathways remove phosphorylated MLKL from the plasma membrane to avert necroptosis. Exit the necroptosis executioner In cells dying by necroptosis, the pseudokinase MLKL becomes phosphorylated and competent to rupture the plasma membrane.… read more here.

Keywords: flotillin; necroptosis; phosphorylated mlkl; membrane ... See more keywords

Flotillin-2 predicts poor prognosis and promotes tumor invasion in intrahepatic cholangiocarcinoma

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recommendations! Published in 2020 at "Oncology Letters"

DOI: 10.3892/ol.2020.11349

Abstract: Intrahepatic cholangiocarcinoma (iCCA) is a highly malignant neoplasm arising from the intrahepatic bile ducts. As a scaffold protein of lipid rafts, flotillin-2 is upregulated in several types of cancer and promotes tumor progression and metastasis.… read more here.

Keywords: flotillin; poor prognosis; invasion; intrahepatic cholangiocarcinoma ... See more keywords