Restoration of proximal tubule flow–activated transport prevents cyst growth in polycystic kidney disease
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DOI: 10.1172/jci.insight.146041
Abstract: Flow-activated Na+ and HCO3– transport in kidney proximal tubules (PT) underlies relatively constant fractional reabsorption during changes in glomerular filtration rate (GFR) or glomerulotubular balance (GTB). In view of hypothesized connections of epithelial cilia to… read more here.
Keywords: cyst; flow activated; activated transport; mice ... See more keywords