Typical Cases of Continuous Flow Chemistry in Pharmaceutical Synthesis in 2023‐2024
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202500132
Abstract: Continuous flow chemistry, as an emerging technology and a significant trend in the field of pharmaceutical synthesis, has been increasingly employed in both academic laboratories and miniature industrial workshops to produce various compounds and intermediates. Compared to traditional… read more here.
Keywords: pharmaceutical synthesis; chemistry; flow chemistry; typical cases ... See more keywords
Enabling Technologies in Carbohydrate Chemistry: Automated Glycan Assembly, Flow Chemistry and Data Science
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200607
Abstract: The synthesis of defined oligosaccharides is a complex task. Several enabling technologies have been introduced in the last two decades to facilitate synthetic access to these valuable biomolecules. In this concept, we describe the technological… read more here.
Keywords: automated glycan; assembly flow; chemistry; glycan assembly ... See more keywords
Amide Bonds Meet Flow Chemistry: A Journey into Methodologies and Sustainable Evolution.
Sign Up to like & getrecommendations! Published in 2022 at "ChemSusChem"
DOI: 10.1002/cssc.202200301
Abstract: Invited for this month's cover are Antonella Ilenia Alfano and Margherita Brindisi (University of Naples Federico II) and Heiko Lange (University of Milano Bicocca). The cover image highlights the impact of greener and more sustainable… read more here.
Keywords: chemistry journey; meet flow; bonds meet; chemistry ... See more keywords
Ultrabright and Stable Red Perovskite Nanocrystals in Micro Light-Emitting Diodes Using Flow Chemistry System.
Sign Up to like & getrecommendations! Published in 2025 at "Small"
DOI: 10.1002/smll.202410753
Abstract: Addressing the challenges of the efficiency and stability of red perovskite nanocrystals is imperative for the successful deployment of these materials in displays and lighting applications. the structural dynamic changes of red perovskite quantum dots… read more here.
Keywords: chemistry; flow chemistry; perovskite nanocrystals; using flow ... See more keywords
The creation and testing of a fully continuous tubular crystallization device suited for incorporation into flow chemistry setups
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Flow Chemistry"
DOI: 10.1007/s41981-019-00042-z
Abstract: The study presents the use of a continuous crystallization device that can be directly incorporated into flow chemistry setups. Inside this device spontaneous nucleation and growth of organic molecules are controlled and maintained, using Aspirin… read more here.
Keywords: flow chemistry; crystallization device; chemistry;
Extending practical flow chemistry into the undergraduate curriculum via the use of a portable low-cost 3D printed continuous flow system
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Flow Chemistry"
DOI: 10.1007/s41981-020-00122-5
Abstract: Continuous flow chemistry is undergoing rapid growth and adoption within the pharmaceutical industry due to its ability to rapidly translate chemical discoveries from medicinal chemistry laboratories into process laboratories. Its growing significance means that it… read more here.
Keywords: flow chemistry; system; chemistry; continuous flow ... See more keywords
Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.02.026
Abstract: Abstract Flow chemistry enables the preparation of bis(indolyl)methanes from various indoles and structurally divergent aldehydes using Sc(OTf) 3 catalysis. The reaction is regioselective for C-3 functionalization of the indoles, occurring over short reaction times allowing… read more here.
Keywords: indolyl methanes; flow chemistry; chemistry; bis indolyl ... See more keywords
Emerging Trends in Flow Chemistry and Applications to the Pharmaceutical Industry.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b01760
Abstract: The field of flow chemistry has garnered considerable attention over the past 2 decades. This Perspective highlights many recent advances in the field of flow chemistry and discusses applications to the pharmaceutical industry, from discovery… read more here.
Keywords: flow chemistry; pharmaceutical industry; chemistry; emerging trends ... See more keywords
Continuous Flow Chemistry and Bayesian Optimization for Polymer-Functionalized Carbon Nanotube-Based Chemiresistive Methane Sensors
Sign Up to like & getrecommendations! Published in 2024 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.4c14279
Abstract: We report the preparation of poly(ionic) polymer-wrapped single-walled carbon nanotube dispersions for chemiresistive methane (CH4) sensors with improved humidity tolerance. Single-walled CNTs (SWCNTs) were noncovalently functionalized by poly(4-vinylpyridine) (P4VP) with varied amounts of a poly(ethylene… read more here.
Keywords: chemistry; flow chemistry; carbon nanotube; continuous flow ... See more keywords
General, Modular Access toward Immobilized Chiral Phosphoric Acid Catalysts and Their Application in Flow Chemistry
Sign Up to like & getrecommendations! Published in 2024 at "ACS Catalysis"
DOI: 10.1021/acscatal.4c00985
Abstract: Chiral phosphoric acids (CPAs) are among the most frequently used organocatalysts, with an ever-increasing number of applications. However, these catalysts are only obtained in a multistep synthesis and are poorly recyclable, which significantly deteriorates their… read more here.
Keywords: spectroscopy; chemistry; flow chemistry; chiral phosphoric ... See more keywords
Catalytically Active Inclusion Bodies─Benchmarking and Application in Flow Chemistry.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00035
Abstract: In industries, enzymes are often immobilized to obtain stable preparations that can be utilized in batch and flow processes. In contrast to traditional immobilization methods that rely on carrier binding, various immobilization strategies have been… read more here.
Keywords: chemistry; flow; inclusion bodies; flow chemistry ... See more keywords