From flow focusing to vortex formation in crossing microchannels
Sign Up to like & getrecommendations! Published in 2017 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-017-1975-7
Abstract: The paper is concerned with the experimental and numerical investigations of the vortex formation and flow focusing inside a cross-shaped microchannel domain. The local hydrodynamics in the junction area, upstream of the focusing region, is… read more here.
Keywords: vortex formation; focusing vortex; formation crossing; flow ... See more keywords
Cell encapsulation modes in a flow-focusing microchannel: effects of shell fluid viscosity
Sign Up to like & getrecommendations! Published in 2019 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-019-2196-z
Abstract: Flow-focusing microencapsulation is an important process to protect the cells in biomedical applications. This article characterizes different cell encapsulation modes and presents the droplet volume distribution, frequency of encapsulation and cell population in terms of… read more here.
Keywords: droplet; encapsulation; cell encapsulation; cell ... See more keywords
In Vitro Sonothrombolysis Enhancement by Transiently Stable Microbubbles Produced by a Flow-Focusing Microfluidic Device
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-017-1965-7
Abstract: Therapeutic approaches that enhance thrombolysis by combining recombinant tissue plasminogen activator (rtPA), ultrasound, and/or microbubbles (MBs) are known as sonothrombolysis techniques. To date, sonothrombolysis approaches have primarily utilized commercially available MB formulations (or derivatives thereof)… read more here.
Keywords: sonothrombolysis; vitro sonothrombolysis; microfluidic device; focusing microfluidic ... See more keywords
Three-dimensional numerical simulation of droplet formation in a microfluidic flow-focusing device
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Brazilian Society of Mechanical Sciences and Engineering"
DOI: 10.1007/s40430-019-1767-y
Abstract: Three-dimensional numerical simulation is performed to study the formation mechanism and influencing factors of droplets in a microfluidic flow-focusing device (MFFD). Three types of liquid–liquid two-phase flow patterns include squeezing, dripping and jetting. Through the… read more here.
Keywords: formation; droplet; flow focusing; phase ... See more keywords
Role of local geometry on droplet formation in axisymmetric microfluidics
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2017.01.022
Abstract: Abstract An unsteady model of droplet formation in co-flow and flow-focusing microfluidics is developed and numerically analyzed to investigate the dynamic behaviors of droplet formation in axisymmetric microfluidics with a focus on the role of… read more here.
Keywords: droplet formation; formation; geometry; focusing microfluidics ... See more keywords
The effect of liquid viscosity on bubble formation dynamics in a flow-focusing device
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Multiphase Flow"
DOI: 10.1016/j.ijmultiphaseflow.2019.05.010
Abstract: Abstract The bubble formation in highly viscous liquids in a microfluidic flow-focusing device is highlighted. The influences of viscosity and flow rate of liquid phase on the bubble formation are studied. The glycerol-water solution (94–1000 mPa s)… read more here.
Keywords: formation; liquid viscosity; flow focusing; bubble formation ... See more keywords
Dynamics of droplet in flow-focusing microchannel under AC electric fields
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Multiphase Flow"
DOI: 10.1016/j.ijmultiphaseflow.2020.103212
Abstract: Abstract Electric field has been proven to be an effective active technique in microfluidic devices for precise manipulating of the microdroplet. In this article, we investigate the Water in Oil droplet formation in a flow-focusing… read more here.
Keywords: field; droplet formation; electric field; flow focusing ... See more keywords
Continuous Production of the Nanoscale Liposome in a Double Flow-Focusing Microfluidic Device
Sign Up to like & getrecommendations! Published in 2019 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.9b04079
Abstract: In the present study, a double flow-focusing platform is applied to evaluate the application of microfluidic devices for the synthesis of liposomes with a uniform size distribution. The size, polydispersity index (PDI), and size distribution… read more here.
Keywords: continuous production; flow focusing; double flow; size ... See more keywords
Generation and characterization of monodisperse deformable alginate and pNIPAM microparticles with a wide range of shear moduli.
Sign Up to like & getrecommendations! Published in 2017 at "Soft matter"
DOI: 10.1039/c7sm01079f
Abstract: Monodisperse particles of varying size, shape, and deformability were produced using two microfluidic strategies. For both strategies, monodisperse emulsion droplets of a crosslinkable solution were generated via flow-focusing. Subsequently, droplets were crosslinked either on chip… read more here.
Keywords: alginate; range; pnipam; flow focusing ... See more keywords
Droplet-based microfluidic synthesis of nanogels for controlled drug delivery: tailoring nanomaterial properties via pneumatically actuated flow-focusing junction.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr00827k
Abstract: Conventional batch syntheses of polymer-based nanoparticles show considerable shortcomings in terms of scarce control over nanomaterials morphology and limited lot-to-lot reproducibility. Droplet-based microfluidics represents a valuable strategy to overcome these constraints, exploiting the formation of… read more here.
Keywords: droplet based; drug; flow focusing; drug delivery ... See more keywords
Beating Poisson stochastic particle encapsulation in flow-focusing microfluidic devices using viscoelastic liquids.
Sign Up to like & getrecommendations! Published in 2022 at "Soft matter"
DOI: 10.1039/d2sm00935h
Abstract: The encapsulation and co-encapsulation of particles in microfluidic flows is essential in applications related to single-cell analysis and material synthesis. However, the whole encapsulation process is stochastic in nature, and its efficiency is limited by… read more here.
Keywords: microfluidic devices; flow focusing; viscoelastic liquids; encapsulation ... See more keywords