Leloir glycosyltransferases enabled to flow synthesis: Continuous production of the natural C‐glycoside nothofagin
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27908
Abstract: C‐glycosyltransferase (CGT) and sucrose synthase (SuSy), each fused to the cationic binding module Zbasic2, were co‐immobilized on anionic carrier (ReliSorb SP400) and assessed for continuous production of the natural C‐glycoside nothofagin. The overall reaction was… read more here.
Keywords: continuous production; flow synthesis; glycoside nothofagin; production natural ... See more keywords
Continuous-Flow Synthesis of Supported Magnetic Iron Oxide Nanoparticles for Efficient Isoeugenol Conversion into Vanillin.
Sign Up to like & getrecommendations! Published in 2018 at "ChemSusChem"
DOI: 10.1002/cssc.201701884
Abstract: This work presents the synthesis of iron oxide nanocatalysts supported on mesoporous Al-SBA-15 by using a continuous-flow setup. The magnetic nanomaterials were tested as catalysts in the oxidative disruption of isoeugenol by using hydrogen peroxide… read more here.
Keywords: synthesis supported; flow synthesis; continuous flow; iron oxide ... See more keywords
Continuous-Flow Synthesis of Phenothiazine Antipsychotics: A Feasibility Study
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201801689
Abstract: The continuous flow synthesis of a model phenothiazine antipsychotic is presented herein, using 3-chloropropionyl chloride as a central building block. The basic phenothiazine-derived scaffold is (atom)-efficiently and mildly synthesized with the aim to present continuous… read more here.
Keywords: flow synthesis; phenothiazine; continuous flow; phenothiazine antipsychotics ... See more keywords
Scalable microwave-assisted continuous flow synthesis of CuO nanoparticles and their thermal conductivity applications as nanofluids
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Powder Technology"
DOI: 10.1016/j.apt.2018.10.001
Abstract: Abstract We have demonstrated the novel and scalable synthesis of CuO nanoparticles by an integration of microwave and flow synthesis. The shape and size of CuO nanoparticles were tuned by changing the concentration of copper… read more here.
Keywords: cuo; flow synthesis; cuo nanoparticles; synthesis cuo ... See more keywords
Engineering of continuous bienzymatic cascade process using monolithic microreactors – In flow synthesis of trehalose
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.131439
Abstract: Abstract Here, we present a two-step continuous flow enzymatic synthesis process in monolithic microreactors using basic sugars as substrates. In the first step UDP-glucose pyrophosphorylase (TaGalU) catalyses the synthesis of uridine-diphosphate-glucose (UDP-Glc) using uridine triphosphate… read more here.
Keywords: synthesis; flow synthesis; process; engineering ... See more keywords
A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.02.017
Abstract: Abstract A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant has been developed. Using this procedure, a variety of nitriles could be smoothly transformed into the desired primary amides… read more here.
Keywords: amides hydrolysis; flow synthesis; synthesis primary; hydrolysis nitriles ... See more keywords
Continuous-Flow Synthesis of Zn1-xMnxS Nanoparticles at Ambient Conditions.
Sign Up to like & getrecommendations! Published in 2024 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.4c01629
Abstract: With its large direct band gap and good chemical stability, ZnS is suitable for many applications, including light-emitting diodes, panel displays, and photodetection. Here, nanoparticles of ZnS are synthesized phase pure under ambient conditions by… read more here.
Keywords: zn1 xmnxs; ambient conditions; continuous flow; flow synthesis ... See more keywords
Automated Flow Synthesis of Peptide–PNA Conjugates
Sign Up to like & getrecommendations! Published in 2022 at "ACS Central Science"
DOI: 10.1021/acscentsci.1c01019
Abstract: Antisense peptide nucleic acids (PNAs) have yet to translate to the clinic because of poor cellular uptake, limited solubility, and rapid elimination. Cell-penetrating peptides (CPPs) covalently attached to PNAs may facilitate clinical development by improving… read more here.
Keywords: peptide; pna conjugates; automated flow; peptide pna ... See more keywords
Efficient and Versatile Flow Synthesis of New Nonionic Glucamide Surfactants
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.4c09871
Abstract: Surfactants are virtually used across all industries where they can fulfill a multitude of roles, such as detergents, emulsifiers, and dispersants, as well as wetting, foaming, and flotation agents. N-Acyl-N-alkyl-d-glucamides are nonionic surfactants that can… read more here.
Keywords: glucamide; efficient versatile; new nonionic; flow synthesis ... See more keywords
Automated Flow Synthesis of Artificial Heme Enzymes for Enantiodivergent Biocatalysis.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c13832
Abstract: The remarkable efficiency with which enzymes catalyze small-molecule reactions has driven their widespread application in organic chemistry. Here, we employ automated fast-flow solid-phase synthesis to access catalytically active full-length enzymes without restrictions on the number… read more here.
Keywords: automated flow; amino acids; synthesis; biocatalysis ... See more keywords
Multi-step continuous-flow synthesis.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Society reviews"
DOI: 10.1039/c6cs00830e
Abstract: Organic chemistry is continually evolving to improve the syntheses of value added and bioactive compounds. Through this progression, a concomitant advancement in laboratory technology has occurred. Many researchers now choose to mediate transformations in continuous-flow… read more here.
Keywords: step continuous; step; flow systems; flow synthesis ... See more keywords