Leloir glycosyltransferases enabled to flow synthesis: Continuous production of the natural C‐glycoside nothofagin
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27908
Abstract: C‐glycosyltransferase (CGT) and sucrose synthase (SuSy), each fused to the cationic binding module Zbasic2, were co‐immobilized on anionic carrier (ReliSorb SP400) and assessed for continuous production of the natural C‐glycoside nothofagin. The overall reaction was… read more here.
Keywords: continuous production; flow synthesis; glycoside nothofagin; production natural ... See more keywords
Continuous-Flow Synthesis of Supported Magnetic Iron Oxide Nanoparticles for Efficient Isoeugenol Conversion into Vanillin.
Sign Up to like & getrecommendations! Published in 2018 at "ChemSusChem"
DOI: 10.1002/cssc.201701884
Abstract: This work presents the synthesis of iron oxide nanocatalysts supported on mesoporous Al-SBA-15 by using a continuous-flow setup. The magnetic nanomaterials were tested as catalysts in the oxidative disruption of isoeugenol by using hydrogen peroxide… read more here.
Keywords: synthesis supported; flow synthesis; continuous flow; iron oxide ... See more keywords
Continuous-Flow Synthesis of Phenothiazine Antipsychotics: A Feasibility Study
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DOI: 10.1002/ejoc.201801689
Abstract: The continuous flow synthesis of a model phenothiazine antipsychotic is presented herein, using 3-chloropropionyl chloride as a central building block. The basic phenothiazine-derived scaffold is (atom)-efficiently and mildly synthesized with the aim to present continuous… read more here.
Keywords: flow synthesis; phenothiazine; continuous flow; phenothiazine antipsychotics ... See more keywords
Scalable microwave-assisted continuous flow synthesis of CuO nanoparticles and their thermal conductivity applications as nanofluids
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Powder Technology"
DOI: 10.1016/j.apt.2018.10.001
Abstract: Abstract We have demonstrated the novel and scalable synthesis of CuO nanoparticles by an integration of microwave and flow synthesis. The shape and size of CuO nanoparticles were tuned by changing the concentration of copper… read more here.
Keywords: cuo; flow synthesis; cuo nanoparticles; synthesis cuo ... See more keywords
Engineering of continuous bienzymatic cascade process using monolithic microreactors – In flow synthesis of trehalose
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.131439
Abstract: Abstract Here, we present a two-step continuous flow enzymatic synthesis process in monolithic microreactors using basic sugars as substrates. In the first step UDP-glucose pyrophosphorylase (TaGalU) catalyses the synthesis of uridine-diphosphate-glucose (UDP-Glc) using uridine triphosphate… read more here.
Keywords: synthesis; flow synthesis; process; engineering ... See more keywords
A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.02.017
Abstract: Abstract A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant has been developed. Using this procedure, a variety of nitriles could be smoothly transformed into the desired primary amides… read more here.
Keywords: amides hydrolysis; flow synthesis; synthesis primary; hydrolysis nitriles ... See more keywords
Automated Flow Synthesis of Peptide–PNA Conjugates
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DOI: 10.1021/acscentsci.1c01019
Abstract: Antisense peptide nucleic acids (PNAs) have yet to translate to the clinic because of poor cellular uptake, limited solubility, and rapid elimination. Cell-penetrating peptides (CPPs) covalently attached to PNAs may facilitate clinical development by improving… read more here.
Keywords: peptide; pna conjugates; automated flow; peptide pna ... See more keywords
Multi-step continuous-flow synthesis.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Society reviews"
DOI: 10.1039/c6cs00830e
Abstract: Organic chemistry is continually evolving to improve the syntheses of value added and bioactive compounds. Through this progression, a concomitant advancement in laboratory technology has occurred. Many researchers now choose to mediate transformations in continuous-flow… read more here.
Keywords: step continuous; step; flow systems; flow synthesis ... See more keywords
The Yin and Yang of coordinating co-solvents in the size-tuning of Fe3O4 nanocrystals through flow synthesis.
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c7nr06291e
Abstract: The present study reports a continuous flow synthesis of differently sized Fe3O4 nanocrystals stabilized by oleylamine and oleic acid. Oleylamine and oleic acid are particularly investigated to elucidate their roles in tailoring the size and… read more here.
Keywords: yin yang; yang coordinating; flow synthesis; size ... See more keywords
Continuous flow synthesis of amines from the cascade reactions of nitriles and carbonyl-containing compounds promoted by Pt-modified titania catalysts
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DOI: 10.1039/c8gc03037e
Abstract: A Pt-modified titania-based catalyst was successfully applied in the synthesis of amines employing several carbonyl containing molecules and nitriles. read more here.
Keywords: modified titania; flow synthesis; continuous flow; synthesis amines ... See more keywords
Integrated plug flow synthesis and crystallisation of pyrazinamide
Sign Up to like & getrecommendations! Published in 2018 at "Reaction Chemistry and Engineering"
DOI: 10.1039/c8re00087e
Abstract: We report the integration of flow chemistry with plug flow crystallisation. Catalytic flow hydration of pyrazinecarbonitrile to pyrazinamide was performed in a packed bed column of MnO2. The effluent of this flow reactor was directly… read more here.
Keywords: chemistry; flow synthesis; synthesis crystallisation; plug flow ... See more keywords