Role of 18F-FLT PET/CT in suspected recurrent or residual lymphoma: final results of a pilot prospective trial
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04323-6
Abstract: PurposeTo evaluate the role of F-18-Fluorothymidine (FLT) PET/CT in lymphoma patients with suspected recurrent or residual disease.MethodsAdult lymphoma patients presenting with positive or equivocal F-18-FDG PET/CT at end-treatment or follow-up were prospectively addressed to an… read more here.
Keywords: lymphoma; flt pet; recurrent residual; flt ... See more keywords
Triphosphate Prodrugs of the Anti-HIV-Active Compound 3'-Deoxy-3'-fluorothymidine (FLT).
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00665
Abstract: 3'-Fluoro-3'-deoxythymidine (FLT) was identified as one of the most potent inhibitors of human immunodeficiency virus (HIV) replication. However, FLT also showed severe toxicity so that it was abundant as a potential chemotherapeutic agent. Here, we… read more here.
Keywords: triphosphate prodrugs; flt; hiv active; prodrugs anti ... See more keywords
Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b10320
Abstract: The receptor tyrosine kinase FLT-3 is frequently mutated in acute myeloid leukemia; however, current small molecule inhibitors suffer from limited efficacy in the clinic. Conversion of a FLT-3 inhibitor (quizartinib) into a proteolysis targeting chimera… read more here.
Keywords: targeting chimera; flt; flt itd; proteolysis targeting ... See more keywords
Multiparametric prediction of pulmonary occupying lesion benignancy: combining 18F-fluorodeoxyglucose and 18F-fluorothymidine PET radiomics with metabolic and clinical features.
Sign Up to like & getrecommendations! Published in 2025 at "Nuclear medicine communications"
DOI: 10.1097/mnm.0000000000002072
Abstract: BACKGROUND This study evaluates the diagnostic value of PET/computed tomography imaging features using dual tracers, 18F-fluorodeoxyglucose (18F-FDG) and 18F-fluorothymidine (18F-FLT), combined with metabolic parameters and clinical characteristics, to differentiate benign and malignant pulmonary occupying lesions… read more here.
Keywords: 18f fluorothymidine; 18f fluorodeoxyglucose; fluorodeoxyglucose 18f; pet ... See more keywords
Federated Learning with Taskonomy for Non-IID Data
Sign Up to like & getrecommendations! Published in 2022 at "IEEE transactions on neural networks and learning systems"
DOI: 10.1109/tnnls.2022.3152581
Abstract: Classical federated learning approaches incur significant performance degradation in the presence of non-independent and identically distributed (non-IID) client data. A possible direction to address this issue is forming clusters of clients with roughly IID data.… read more here.
Keywords: non iid; federated learning; learning taskonomy; taskonomy non ... See more keywords
RNA activating-double stranded RNA targeting flt-1 promoter inhibits endothelial cell proliferation through soluble FLT-1 upregulation
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0193590
Abstract: Short-activating RNA (saRNA), which targets gene promoters, has been shown to increase the target gene expression. In this study, we describe the use of an saRNA (Flt a-1) to target the flt-1 promoter, leading to… read more here.
Keywords: flt promoter; flt; endothelial cell; rna ... See more keywords
Vascular Endothelial Growth Factor Receptor, fms-Like Tyrosine Kinase-1 (Flt-1), as a Novel Binding Partner for SARS-CoV-2 Spike Receptor-Binding Domain
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.906063
Abstract: Angiotensin-converting enzyme 2 (ACE2) and neuropilin 1, a vascular endothelial growth factor (VEGF) receptor, were identified to bind to the SARS-CoV-2 spike receptor-binding domain (spike RBD). In silico analysis based on 3D structure, multiple sequence… read more here.
Keywords: flt; rbd; rspike rbd; receptor ... See more keywords
PlGF/FLT-1 deficiency leads to reduced STAT3-C/EBPβ signaling and aberrant polarization in decidual macrophages during early spontaneous abortion
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1061949
Abstract: Introduction Dysregulated macrophage polarization (excessive M1-like or limited M2-like macrophages) in the early decidua contributes to allogeneic fetal rejection and thus early spontaneous abortion. However, the modulators of M1/M2 balance at the early maternal-fetal interface… read more here.
Keywords: spontaneous abortion; flt; abortion; plgf ... See more keywords
Effect of Pressing Process on Metabolomics Profiling and Sensory Properties: A Comparative Study of Fu Brick Tea Versus Fu Loose Tea from Identical Raw Dark Tea
Sign Up to like & getrecommendations! Published in 2025 at "Foods"
DOI: 10.3390/foods14173053
Abstract: Fu tea is a unique microbially fermented tea from China, and has two types. The primary distinction between these two types—Fu brick tea (FBT) and Fu loose tea (FLT)—is that FBT is compressed into bricks,… read more here.
Keywords: raw dark; brick tea; tea; dark tea ... See more keywords