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Published in 2017 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-017-0381-2
Abstract: Internal tandem duplications (ITD) and tyrosine-kinase domain (TKD) mutations of the FMS-like tyrosine-kinase 3 (FLT3) can be found in up to one third of patients with acute myeloid leukemia (AML) and confer a poor prognosis.…
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Keywords:
targeting flt3;
future targeting;
flt3 activation;
activation aml ... See more keywords