FLT3 ligand plasma levels have no impact on outcomes after allotransplant in acute leukemia.
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2019.04.015
Abstract: OBJECTIVE This study was designed to assess the impact on outcomes of early soluble Fms-like tyrosine kinase 3 ligand concentrations (sFLc) in patients receiving an allogeneic hematopoietic stem cell transplantation (allo-HSCT) for acute lymphoblastic leukemia… read more here.
Keywords: allo hsct; acute; impact outcomes; leukemia ... See more keywords
Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo
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DOI: 10.1038/s41598-017-18283-0
Abstract: A common helper-like innate lymphoid precursor (CHILP) restricted to the innate lymphoid cells (ILC) lineage has been recently characterized. While specific requirements of transcription factors for CHILPs development has been partially described, their ability to… read more here.
Keywords: flt3l levels; bona fide; innate lymphoid; lymphoid ... See more keywords
Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses
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DOI: 10.1038/s41598-018-30631-2
Abstract: Enterovirus A71 (EV-A71) infection can induce encephalitis, which causes death or long-term neurological sequelae, especially in young children. Using a murine infection model, we searched for anti-EV-A71 agents, because effective therapies are not available to… read more here.
Keywords: enterovirus a71; infection; mice; ligand ... See more keywords
Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.27222
Abstract: Therapeutic effects of FLT3 inhibitors have been reported in acute myeloid leukemia (AML) with constitutively activating FLT3 mutations, including internal tandem duplication (ITD) and point mutation, which are found in approximately one-third of AML patients.… read more here.
Keywords: flt3; effect; gilteritinib flt3; flt3 inhibitors ... See more keywords