Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 Inhibitors.
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DOI: 10.1158/2643-3230.bcd-20-0143
Abstract: Despite promising results with FLT3 inhibitors (FLT3i), response durations remain short. We studied pretreatment and relapse bone marrow samples from patients with FLT3-mutated acute myeloid leukemia (AML) treated with FLT3i-based therapies (secondary resistance cohort), and… read more here.
Keywords: flt3 inhibitors; flt3i based; resistance; treated type ... See more keywords