Inhibitor bias in luciferase-based luminescence assays
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DOI: 10.2144/fsoa-2020-0081
Abstract: The firefly luciferase (FLuc)-based bioluminescent reaction [1] provides the basis for one of the most popular detection systems in high-throughput screening (HTS) [2], especially for cell-based (reporter gene) assays [2,3]. Bioluminescence results from the activity… read more here.
Keywords: reporter; luminescence signal; inhibition; fluc inhibition ... See more keywords