The Effect of Flucloxacillin on Warfarin Anticoagulation: A Swedish Register-Based Nationwide Cohort Study.
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DOI: 10.1055/s-0039-1693462
Abstract: BACKGROUND Data indicate that codispensing flucloxacillin to patients already on warfarin may result in decreased warfarin efficacy. OBJECTIVES This article investigates the effect of flucloxacillin on warfarin anticoagulation. PATIENTS AND METHODS In a retrospective cohort… read more here.
Keywords: week; warfarin; treatment; effect flucloxacillin ... See more keywords
Development and validation of an UPLC–MS/MS assay for the simultaneous quantification of seven commonly used antibiotics in human plasma and its application in therapeutic drug monitoring
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DOI: 10.1093/jac/dkae047
Abstract: Abstract Objective To develop and validate an UPLC–MS/MS assay for simultaneous determination of the total concentration of ceftazidime, ciprofloxacin, flucloxacillin, piperacillin, tazobactam, sulfamethoxazole, N-acetyl sulfamethoxazole and trimethoprim, and the protein-unbound concentration of flucloxacillin, in human… read more here.
Keywords: human plasma; within day; uplc assay; day ... See more keywords
Intravenous flucloxacillin treatment is associated with a high incidence of hypokalaemia
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DOI: 10.1111/bcp.13969
Abstract: Intravenous flucloxacillin is one of the most frequently used high‐dose penicillin therapies in hospitalized patients, forming the cornerstone treatment of invasive Staphylococcus aureus infection. Being a nonreabsorbable anion, flucloxacillin has been suggested to cause hypokalaemia,… read more here.
Keywords: treatment; incidence hypokalaemia; flucloxacillin; hypokalaemia ... See more keywords
Hypokalemia in patients treated with intravenous flucloxacillin: incidence and risk factors.
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DOI: 10.1111/bcp.15236
Abstract: INTRODUCTION Hypokalemia is a potentially life-threatening adverse event of flucloxacillin with unknown incidence. The risk of flucloxacillin-induced hypokalemia has recently been suggested to be increased among females compared to males. The aim of this study… read more here.
Keywords: intravenous flucloxacillin; flucloxacillin; incidence; hypokalemia ... See more keywords