Emergence of clonal fluconazole-resistant Candida parapsilosis clinical isolates in a multicentre laboratory-based surveillance study in India
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkz029
Abstract: Objectives The emergence of fluconazole resistance in Candida parapsilosis healthcare-associated infections has recently been increasingly reported. Antifungal susceptibility profiles and mechanisms of fluconazole resistance in C. parapsilosis (n = 199) from nine hospitals in India collected over… read more here.
Keywords: candida parapsilosis; parapsilosis; fluconazole resistant; non susceptible ... See more keywords
Promising antifungal properties of the orally active autophagy inhibitor SBP-7455 against fluconazole-resistant Candida clinical isolates.
Sign Up to like & getrecommendations! Published in 2025 at "Letters in applied microbiology"
DOI: 10.1093/lambio/ovaf055
Abstract: Candida species, the single most common cause of fungal infections, are major opportunistic pathogens. Novel antifungal agents are needed to address the threat of Candida infections resistant to first-line antifungal agents and those that are… read more here.
Keywords: sbp 7455; autophagy inhibitor; sbp; fluconazole resistant ... See more keywords
Fluconazole-Resistant Candida Albicans Vaginal Infections at a Referral Center and Treated With Boric Acid.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of lower genital tract disease"
DOI: 10.1097/lgt.0000000000000733
Abstract: OBJECTIVE The authors investigate the incidence of clinical and mycological resistance of Candida albicans vulvovaginitis (VVC) at the Jefferson Vulvovaginal Health Center. They also review their experience with boric acid in the treatment of fluconazole-resistant… read more here.
Keywords: boric acid; fluconazole resistant; candida albicans; center ... See more keywords
Antifungal activity and potential mechanism of berberine hydrochloride against fluconazole-resistant Candida albicans.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001542
Abstract: Introduction. The emergence of resistance to fluconazole in Candida albicans has made the clinical treatment of this microbe difficult. A potential strategy to address this problem involves diminishing fungal resistance to antimicrobial drugs.Hypothesis. Berberine hydrochloride… read more here.
Keywords: fluconazole resistant; hog mapk; mapk pathway; berberine hydrochloride ... See more keywords
Promising activity of etomidate against mixed biofilms of fluconazole-resistant Candida albicans and methicillin-resistant Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001810
Abstract: Introduction. Candida albicans and Staphylococcus aureus are recognized for their development of resistance and biofilm formation. New therapeutic alternatives are necessary in this context.Hypothesis. Etomidate shows potential application in catheters against mixed biofilms of fluconazole-resistant… read more here.
Keywords: mixed biofilms; candida albicans; albicans methicillin; biofilms fluconazole ... See more keywords
Fluconazole‐resistant Candida parapsilosis genotypes from hospitals located in five Spanish cities and one in Italy: Description of azole‐resistance profiles associated with the Y132F ERG11p substitution
Sign Up to like & getrecommendations! Published in 2024 at "Mycoses"
DOI: 10.1111/myc.13706
Abstract: Fluconazole‐resistant Candida parapsilosis is a matter of concern. read more here.
Keywords: fluconazole resistant; resistant candida; parapsilosis genotypes; candida parapsilosis ... See more keywords
Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00584-17
Abstract: ABSTRACT The pathogenic yeast Candida albicans can develop resistance to the widely used antifungal agent fluconazole, which inhibits ergosterol biosynthesis. Resistance is often caused by gain-of-function mutations in the transcription factors Mrr1 and Tac1, which… read more here.
Keywords: resistant clinical; drug; fluconazole resistant; resistance ... See more keywords
Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00710-22
Abstract: We have been monitoring the antifungal resistance in Candida parapsilosis isolates collected from inpatients at Madrid metropolitan area hospitals for the last 3 years. The study aimed to elucidate the presence of fluconazole-resistant C. parapsilosis… read more here.
Keywords: substitution; parapsilosis genotypes; parapsilosis; fluconazole resistant ... See more keywords
Hospital Clonal Outbreak of Fluconazole-Resistant Candida parapsilosis Harboring the Y132F ERG11p Substitution in a French Intensive Care Unit
Sign Up to like & getrecommendations! Published in 2023 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01130-22
Abstract: We report the first identification of a fluconazole-resistant Candida parapsilosis (FR-Cp) strain in our hospital, which subsequently caused an outbreak involving 17 patients (12 deaths) within a 26-bed French intensive care unit. Microsatellite genotyping confirmed… read more here.
Keywords: fluconazole resistant; candida; french intensive; resistant candida ... See more keywords
Antifungal activity of silver nanoparticles on Fluconazole resistant Dermatophytes identified by (GACA)4 and isolated from primary school children suffering from Tinea Capitis in Ismailia - Egypt.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2017.63.11.12
Abstract: Fungal infections caused by dermatophytes recently became more common. Available antifungal drugs are limited because of emergence of resistant strains due to prophylaxis with them, so there is an urgent need for novel antifungals. This… read more here.
Keywords: silver nanoparticles; fluconazole resistant; resistant dermatophytes; antifungal activity ... See more keywords
Inhibitory effect of menthol on expression of aspartyl proteinase 1 in fluconazole-resistant Candida albicans
Sign Up to like & getrecommendations! Published in 2019 at "Journal of HerbMed Pharmacology"
DOI: 10.15171/jhp.2019.06
Abstract: Introduction: Fluconazole-resistant Candida albicans is one of the biggest problems faced in clinical practice. Using of natural pure compounds such as menthol could be one of the most frequently ways to solve this problem. The… read more here.
Keywords: fluconazole resistant; candida albicans; expression; resistant candida ... See more keywords