Low‐dose fludarabine and cyclophosphamide combined with standard dose rituximab (LD‐FCR) is an effective and safe regimen for elderly untreated patients with chronic lymphocytic leukemia: The Israeli CLL study group experience
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DOI: 10.1002/hon.2580
Abstract: Chronic lymphocytic leukemia (CLL) is a disease of elderly patients. The fludarabine, cyclophosphamide, and rituximab (FCR) regimen is considered the treatment of choice for young fit patients with CLL; however, this combination is toxic for… read more here.
Keywords: rituximab; cll; study; fludarabine cyclophosphamide ... See more keywords
Obinutuzumab plus fludarabine and cyclophosphamide in previously untreated, fit patients with chronic lymphocytic leukemia: a subgroup analysis of the GREEN study
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DOI: 10.1038/s41375-019-0554-1
Abstract: GREEN (NCT01905943) is a nonrandomized, open-label, single-arm, phase 3b study investigating the safety and efficacy of obinutuzumab alone or in combination with chemotherapy in chronic lymphocytic leukemia (CLL). We report the preplanned subgroup analysis of… read more here.
Keywords: lymphocytic leukemia; analysis; previously untreated; subgroup analysis ... See more keywords
Ibrutinib, fludarabine, cyclophosphamide, and obinutuzumab (iFCG) regimen for chronic lymphocytic leukemia (CLL) with mutated IGHV and without TP53 aberrations
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DOI: 10.1038/s41375-021-01280-8
Abstract: Chemoimmunotherapy with combined fludarabine, cyclophosphamide and rituximab (FCR) has been an effective treatment for patients with chronic lymphocytic leukemia (CLL). We initiated a phase II trial for previously untreated patients with CLL with mutated IGHV… read more here.
Keywords: mutated ighv; leukemia; fludarabine cyclophosphamide; cll mutated ... See more keywords
Aplastic Anemia Preconditioned with Fludarabine, Cyclophosphamide, and Anti-Thymocyte Globulin
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DOI: 10.12659/aot.915696
Abstract: Background Graft rejection and graft versus host disease (GvHD) have impeded the success of hematopoietic cell transplantation for severe aplastic anemia (SAA) patients. There is no sufficient data to identify the outcomes of peripheral blood… read more here.
Keywords: fca regimen; aplastic anemia; adult saa; fludarabine cyclophosphamide ... See more keywords