Emerging Cerebrospinal Fluid Biomarkers of Disease Activity and Progression in Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2024.0017
Abstract: This cohort study examines data from 2 prospective multiple sclerosis cohorts to identify cerebrospinal fluid measures associated with relapsing and nonrelapsing progressive multiple sclerosis pathobiology. read more here.
Keywords: multiple sclerosis; cerebrospinal fluid; sclerosis; emerging cerebrospinal ... See more keywords
Cerebrospinal Fluid Biomarkers for Alzheimer Disease Among Patients With Dementia.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2025.0693
Abstract: Importance The defining pathological features of Alzheimer disease (AD) may also be contributing factors in other dementias. Objective To examine the prevalence of β-amyloid (Aβ) and tau pathophysiological changes as indicated by cerebrospinal fluid biomarkers,… read more here.
Keywords: dementia; disease; cerebrospinal fluid; pathology ... See more keywords
Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51681
Abstract: Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by… read more here.
Keywords: biomarkers measured; cerebrospinal fluid; clinical utility; utility cerebrospinal ... See more keywords
MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51730
Abstract: White matter damage is a feature of Alzheimer's disease, yet little is known about how facets of the Alzheimer's disease process relate to key features of white matter structure. We examined the association of Alzheimer's… read more here.
Keywords: mri fluid; reveal determinants; alzheimer disease; biomarkers reveal ... See more keywords
Relationship between cerebrospinal fluid biomarkers and structural brain network properties in Parkinson's disease
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.27284
Abstract: Background: Pathological accumulation of α‐synuclein, amyloid‐β42, and tau proteins in the brain is considered critical for development of various neurodegenerative diseases. read more here.
Keywords: relationship cerebrospinal; fluid biomarkers; biomarkers structural; structural brain ... See more keywords
Drain fluid biomarkers for the diagnosis of clinically relevant postoperative pancreatic fistula - a diagnostic accuracy systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgery"
DOI: 10.1097/js9.0000000000000482
Abstract: BACKGROUND Pancreatectomy is the only curative treatment available for pancreatic cancer and a necessity for patients with challenging pancreatic pathology. To optimise outcomes, postsurgical complications such as clinically relevant postoperative pancreatic fistula (CR-POPF) should be… read more here.
Keywords: fluid biomarkers; drain; meta analysis; drain fluid ... See more keywords
Clinical usefulness of cerebrospinal fluid biomarkers in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13910
Abstract: Alzheimer's disease (AD) is a complex disease that shares clinical features with other dementias. It is important to establish a specific and reliable diagnosis. Nowadays, AD diagnosis is based on cerebrospinal fluid (CSF) biomarkers. However,… read more here.
Keywords: alzheimer disease; usefulness cerebrospinal; cerebrospinal fluid; clinical usefulness ... See more keywords
Fluid biomarkers for amyotrophic lateral sclerosis: a review
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Neurodegeneration"
DOI: 10.1186/s13024-023-00685-6
Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of upper and lower motor neurons. Presently, three FDA-approved drugs are available to help slow functional decline for patients with ALS, but… read more here.
Keywords: review; fluid; amyotrophic lateral; lateral sclerosis ... See more keywords
Characterizing plasma and cerebrospinal fluid biomarkers relevant to neurodegeneration in captive olive baboons (Papio anubis)
Sign Up to like & getrecommendations! Published in 2025 at "PLOS ONE"
DOI: 10.1371/journal.pone.0318173
Abstract: Alzheimer’s disease and related dementias (ADRD) present a significant global disease burden that is only expected to grow in the future. As such, there is a need to develop and investigate biomarkers that identify individuals… read more here.
Keywords: age; cerebrospinal fluid; relevant neurodegeneration; biomarkers relevant ... See more keywords
Big data and artificial intelligence applied to blood and CSF fluid biomarkers in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1459502
Abstract: Artificial intelligence (AI) has meant a turning point in data analysis, allowing predictions of unseen outcomes with precedented levels of accuracy. In multiple sclerosis (MS), a chronic inflammatory-demyelinating condition of the central nervous system with… read more here.
Keywords: blood csf; multiple sclerosis; fluid biomarkers; artificial intelligence ... See more keywords
Role of Body-Fluid Biomarkers in Alzheimer’s Disease Diagnosis
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostics"
DOI: 10.3390/diagnostics10050326
Abstract: Alzheimer’s disease (AD) is a complex neurodegenerative disease that requires extremely specific biomarkers for its diagnosis. For current diagnostics capable of identifying AD, the development and validation of early stage biomarkers is a top research… read more here.
Keywords: fluid biomarkers; alzheimer disease; disease; role ... See more keywords