The rate of fluid shear stress is a potent regulator for the differentiation of mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28296
Abstract: We have previously demonstrated that the rate of fluid shear stress (ΔSS) can manipulate the fate of mesenchymal stem cells (MSCs) to osteogenic or chondrogenic cells. However, whether ΔSS is comparable to other two means… read more here.
Keywords: shear stress; differentiation; fluid shear; rate fluid ... See more keywords
Simulation of intracellular $$\hbox {Ca}^{2+}$$Ca2+ transients in osteoblasts induced by fluid shear stress and its application
Sign Up to like & getrecommendations! Published in 2017 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-016-0833-y
Abstract: Intracellular $$\hbox {Ca}^{2+}$$Ca2+ transient induced by fluid shear stress (FSS) plays an important role in mechanical regulation of osteoblasts, but the cellular mechanism remains incompletely understood. Here, we constructed a mathematical model combined with experiments… read more here.
Keywords: shear stress; induced fluid; intracellular hbox; fluid shear ... See more keywords
Revealing anisotropic elasticity of endothelium under fluid shear stress.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.03.040
Abstract: Endothelium lining interior surface of blood vessels experiences various physical stimulations in vivo. Its physical properties, especially elasticity, play important roles in regulating the physiological functions of vascular systems. In this paper, an integrated approach… read more here.
Keywords: fluid shear; endothelium; direction; shear stress ... See more keywords
Fluid shear stress applied by orbital shaking induces MG-63 osteosarcoma cells to activate ERK in two phases through distinct signaling pathways
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.01.004
Abstract: Fluid shear stress (FSS) induces a series of biochemical responses in osteoblasts, and this “mechanoresponse” regulates their survival, proliferation and differentiation. However, the events in cells immediately after FSS application are unclear, and how biochemical… read more here.
Keywords: orbital shaking; shear stress; method; fluid shear ... See more keywords
The effect of tensile and fluid shear stress on the in vitro degradation of magnesium alloy for stent applications
Sign Up to like & getrecommendations! Published in 2018 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2018.08.002
Abstract: Magnesium alloys have gained great attention as biodegradable materials for stent applications. Cardiovascular stents are continuously exposed to different types of mechanical loadings simultaneously during service, including tensile, compressive and fluid shear stress. In this… read more here.
Keywords: degradation; shear stress; effect; magnesium ... See more keywords
The effects of fluid shear stress and O2 concentration on the phosphorylation of eNOS at Ser635 in endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Synergy"
DOI: 10.1016/j.synres.2019.100046
Abstract: Abstract Under hypoxic conditions, NO plays an important role in regulating O2 delivery by controlling local blood vessel relaxation. NO is primarily produced by endothelial NO synthase (eNOS), which is reportedly phosphorylated at Ser635 and… read more here.
Keywords: fluid shear; stress concentration; stress; phosphorylation enos ... See more keywords
Sialyl Lewisx-P-selectin cascade mediates tumor–mesothelial adhesion in ascitic fluid shear flow
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10334-6
Abstract: Organ-specific colonization suggests that specific cell–cell recognition is essential. Yet, very little is known about this particular interaction. Moreover, tumor cell lodgement requires binding under shear stress, but not static, conditions. Here, we successfully isolate… read more here.
Keywords: selectin cascade; fluid shear; lewisx selectin; sialyl lewisx ... See more keywords
Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32572-2
Abstract: Traumatic brain injury (TBI) elevates Abeta (Aβ) peptides in the brain and cerebral spinal fluid. Aβ peptides are amphipathic molecules that can modulate membrane mechanics. Because the mechanosensitive cation channel PIEZO1 is gated by membrane… read more here.
Keywords: piezo1; shear stress; stress; fluid shear ... See more keywords
Effect of fluid shear stress on in vitro cultured ureteric bud cells
Sign Up to like & getrecommendations! Published in 2018 at "Biomicrofluidics"
DOI: 10.1063/1.5035328
Abstract: Most kidney cells are continuously exposed to fluid shear stress (FSS) from either blood flow or urine flow. Recent studies suggest that changes in FSS could contribute to the function and injury of these kidney… read more here.
Keywords: fss; shear stress; fluid shear; cell ... See more keywords
The effect of fluid shear on oscillating bubbly flows
Sign Up to like & getrecommendations! Published in 2019 at "Physics of Fluids"
DOI: 10.1063/1.5089664
Abstract: The impact of fluid shear on the bubble distribution in channel flows with periodically oscillating pressure gradient is examined by direct numerical simulations. Equal-sized and nearly circular bubbles are placed randomly in the channel at… read more here.
Keywords: bubble distribution; effect; fluid shear; rate ... See more keywords
Stream broadening due to fluid shear across the wider transverse dimension of a free-flow zone electrophoresis channel.
Sign Up to like & getrecommendations! Published in 2019 at "Physics of fluids"
DOI: 10.1063/1.5098460
Abstract: While the pressure-gradient applied along the length of a free-flow zone electrophoresis (FFZE) chamber is known to produce a parabolic flow profile for the carrier electrolyte across the narrower channel dimension (typically the channel depth),… read more here.
Keywords: dimension; stream; channel; fluid shear ... See more keywords