Self-assembly of lipid rafts revealed by fluorescence correlation spectroscopy in living breast cancer cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biophotonics"
DOI: 10.1002/jbio.201900214
Abstract: Lipids and proteins in the plasma membrane are laterally heterogeneous and formalised as lipid rafts featuring unique biophysical properties. However, the self-assembly mechanism of lipid raft cannot be revealed even its physical properties and components… read more here.
Keywords: self assembly; correlation spectroscopy; fluorescence correlation; spectroscopy ... See more keywords
Shining Light on Polymeric Drug Nanocarriers with Fluorescence Correlation Spectroscopy.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202100892
Abstract: The use of nanoparticles as carriers is an extremely promising way for administration of therapeutic agents, such as drug molecules, proteins and nucleic acids. Such nanocarriers (NCs) can increase the solubility of hydrophobic compounds, protect… read more here.
Keywords: spectroscopy; fluorescence correlation; correlation spectroscopy; drug ... See more keywords
Fluorescence Correlation and Cross-Correlation Spectroscopy in Zebrafish.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8772-6_5
Abstract: There has been increasing interest in biophysical studies on live organisms to gain better insights into physiologically relevant biological events at the molecular level. Zebrafish (Danio rerio) is a viable vertebrate model to study such… read more here.
Keywords: fluorescence correlation; correlation; cross correlation; correlation cross ... See more keywords
Studying molecular interactions in the intact organism: fluorescence correlation spectroscopy in the living zebrafish embryo
Sign Up to like & getrecommendations! Published in 2020 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-020-01930-5
Abstract: Cell behaviour and function is determined through the interactions of a multitude of molecules working in concert. To observe these molecular dynamics, biophysical studies have been developed that track single interactions. Fluorescence correlation spectroscopy (FCS)… read more here.
Keywords: studying molecular; correlation spectroscopy; fluorescence correlation; spectroscopy ... See more keywords
Heterogeneity of the Nuclear Environment Investigated by Superresolution Microscopy and Fluorescence Correlation Spectroscopy
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.783
Abstract: Genomes are more than one-dimensional entities purely defined by their linear DNA sequences [Misteli T, Cell (2007)]. A long standing challenge in biology is to decipher the principles of organization of what can be considered,… read more here.
Keywords: resolution; microscopy; correlation spectroscopy; fluorescence correlation ... See more keywords
Anomalous Diffusion in Inverted Variable-Lengthscale Fluorescence Correlation Spectroscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.01.024
Abstract: Using fluorescence correlation spectroscopy (FCS) to distinguish between different types of diffusion processes is often a perilous undertaking because the analysis of the resulting autocorrelation data is model dependant. Two recently introduced strategies, however, can… read more here.
Keywords: correlation spectroscopy; fluorescence correlation; diffusion; spectroscopy ... See more keywords
Fluorescence Correlation Spectroscopy Monitors the Fate of Degradable Nanocarriers in the Blood Stream
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c01407
Abstract: The use of nanoparticles as carriers to deliver pharmacologically active compounds to specific parts of the body via the bloodstream is a promising therapeutic approach for the effective treatment of various diseases. To reach their… read more here.
Keywords: spectroscopy; correlation spectroscopy; fate degradable; fluorescence correlation ... See more keywords
Quantifying Reversible Surface Binding via Surface-Integrated Fluorescence Correlation Spectroscopy
Sign Up to like & getrecommendations! Published in 2018 at "Nano Letters"
DOI: 10.1021/acs.nanolett.8b00875
Abstract: We present a simple and versatile single-molecule-based method for the accurate determination of binding rates to surfaces or surface bound receptors. To quantify the reversible surface attachment of fluorescently labeled molecules, we have modified previous… read more here.
Keywords: correlation spectroscopy; surface; fluorescence correlation; spectroscopy ... See more keywords
Fluorescence correlation spectroscopy reveals a cooperative unfolding of monomeric amyloid-β 42 with a low Gibbs free energy
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-02410-y
Abstract: The amyloid-beta peptide (Aβ) plays a major role in the progression of Alzheimer’s disease. Due to its high toxicity, the 42 amino acid long isoform Aβ42 has become of considerable interest. The Aβ42 monomer is… read more here.
Keywords: correlation spectroscopy; gibbs free; fluorescence correlation; cooperative unfolding ... See more keywords
Fluorescence correlation spectroscopy and fluorescence lifetime imaging microscopy for deciphering the morphological evolution of supramolecular self-assembly.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06607f
Abstract: The properties and functions of non-covalent interaction-driven fluorescent supramolecular self-assembly depend greatly on their evolution dynamics. Electron microscopy, atomic force microscopy, and confocal laser scanning microscopy have been used to elucidate the formation of molecular… read more here.
Keywords: spectroscopy; fluorescence correlation; microscopy; self assembly ... See more keywords
Comparison of nanoparticle diffusion using fluorescence correlation spectroscopy and differential dynamic microscopy within concentrated polymer solutions
Sign Up to like & getrecommendations! Published in 2017 at "Applied Physics Letters"
DOI: 10.1063/1.5016062
Abstract: We studied the diffusion of nanoparticles (NPs) within aqueous entangled solutions of polyethylene oxide (PEO) by using two different optical techniques. Fluorescence correlation spectroscopy, a method widely used to investigate nanoparticle dynamics in polymer solution,… read more here.
Keywords: diffusion; microscopy; correlation spectroscopy; differential dynamic ... See more keywords