Fluorescence-guided laser lithotripsy: Estimation of the potential effectiveness and safety increase based on first clinical data.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biophotonics"
DOI: 10.1002/jbio.202300044
Abstract: In clinically approved laser lithotripsy systems, there is no automatic monitoring of fiber position to date. We investigated whether detecting stone autofluorescence, excited by a green aiming beam, is possible via the fiber during fragmentation… read more here.
Keywords: estimation potential; lithotripsy estimation; guided laser; laser lithotripsy ... See more keywords
SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery.
Sign Up to like & getrecommendations! Published in 2017 at "Surgical oncology"
DOI: 10.1016/j.suronc.2017.03.002
Abstract: PURPOSE Fluorescence-guided surgery (FGS) provides surgeons with new opportunities to improve real-time cancer nodule detection and tumor margin visualization. Currently, the most important challenge in this field is the development of fluorescent dyes that specifically… read more here.
Keywords: sgm 101; antibody; fluorescence guided; guided surgery ... See more keywords
Chemical Decrosslinking-Based Peptide Characterization of Formaldehyde-Fixed Rat Pancreas Using Fluorescence-Guided Single-Cell Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00612
Abstract: Approaches for the characterization of proteins/peptides in single cells of formaldehyde-fixed (FF) tissues via mass spectrometry (MS) are still under development. The lack of a general method for selectively eliminating formaldehyde-induced crosslinking is a major… read more here.
Keywords: cell; mass spectrometry; formaldehyde fixed; fluorescence guided ... See more keywords
Preclinical Evaluation of a Humanized, Near-Infrared Fluorescent Antibody for Fluorescence-Guided Surgery of MUC16-Expressing Pancreatic Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00203
Abstract: Surgery remains the only potentially curative treatment option for pancreatic cancer, but resections are made more difficult by infiltrative disease, proximity of critical vasculature, peritumoral inflammation, and dense stroma. Surgeons are limited to tactile and… read more here.
Keywords: pancreatic cancer; fluorescence guided; cancer; guided surgery ... See more keywords
High-Contrast Detection of Somatostatin Receptor Subtype-2 for Fluorescence-Guided Surgery
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00583
Abstract: Dye design can influence the ability of fluorescently labeled imaging agents to generate tumor contrast and has become an area of significant interest in the field of fluorescence-guided surgery (FGS). Here, we show that the… read more here.
Keywords: contrast; fnir tag; fluorescence guided; somatostatin receptor ... See more keywords
AND-gate contrast agents for enhanced fluorescence-guided surgery.
Sign Up to like & getrecommendations! Published in 2020 at "Nature biomedical engineering"
DOI: 10.1038/s41551-020-00616-6
Abstract: Surgical resection of tumours requires precisely locating and defining the margins between lesions and normal tissue. However, this is made difficult by irregular margin borders. Although molecularly targeted optical contrast agents can be used to… read more here.
Keywords: contrast agents; surgery; gate contrast; contrast ... See more keywords
Fundamentals and developments in fluorescence-guided cancer surgery
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/s41571-021-00548-3
Abstract: Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the past decade as a promising and effective method of intraoperative cancer detection. An impressive number of fluorescently labelled antibodies, peptides, particles and other molecules related… read more here.
Keywords: cancer; fluorescence guided; surgery; tumour targeted ... See more keywords
5-aminolevulinic acid fluorescence guided surgery for resection of cystic meningioma with bone invasion.
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Neurosurgery"
DOI: 10.1080/02688697.2020.1837729
Abstract: Meningiomas have a 5 year recurrence rate of 8%. Histological grade and extent of resection are the two main prognostic factors. Cystic meningiomas represent between 2 and 4% of meningiomas, and the complete resection rate… read more here.
Keywords: bone invasion; guided surgery; fluorescence guided; resection ... See more keywords
Optical Principles of Fluorescence-Guided Brain Tumor Surgery: A Practical Primer for the Neurosurgeon.
Sign Up to like & getrecommendations! Published in 2018 at "Neurosurgery"
DOI: 10.1093/neuros/nyy315
Abstract: Fluorescence-guided surgery is a rapidly growing field that has produced some of the most important innovations in surgical oncology in the past decade. These intraoperative imaging technologies provide information distinguishing tumor tissue from normal tissue… read more here.
Keywords: guided brain; surgery; fluorescence; fluorescence guided ... See more keywords
Can fluorescence-guided surgery improve optimal surgical treatment for ovarian cancer? A systematic scoping review of clinical studies
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2022-003846
Abstract: Background The predicament of achieving optimal surgical intervention faced by surgeons in treating ovarian cancer has driven research into improving intra-operative detection of cancer using fluorescent materials. Objective To provide a literature overview on the… read more here.
Keywords: ovarian cancer; fluorescence guided; cancer; guided surgery ... See more keywords
Fluorescence-guided surgery using indocyanine green in dogs with superficial solid tumours
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary Record"
DOI: 10.1136/vr.105554
Abstract: Background Near-infrared fluorescence (NIRF) imaging is a relatively novel technique that can aid surgeons during intraoperative tumour identification. Methods Nine canine oncology patients (five mammary gland tumours, three mast cell tumours and one melanoma) received… read more here.
Keywords: indocyanine green; fluorescence; tissue; fluorescence guided ... See more keywords