Production of Metal‐Free C, N Alternating Nanoplatelets and Their In Vivo Fluorescence Imaging Performance without Labeling
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DOI: 10.1002/adfm.202004800
Abstract: The use of luminescent probes with proper optical and morphological properties, high serum stability, low cytotoxicity, and good biocompatibility is a costeffective method for bioimaging. In this work, a route is developed to produce a… read more here.
Keywords: vivo fluorescence; fluorescence; fluorescence imaging; production metal ... See more keywords
Zwitterionic AIEgens: Rational Molecular Design for NIR‐II Fluorescence Imaging‐Guided Synergistic Phototherapy
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DOI: 10.1002/adfm.202007026
Abstract: Fluorescence imaging in the second near‐infrared region (NIR‐II) can penetrate tissue at centimeter depths and obtain high image fidelity. However, facile synthesis of small‐molecule fluorescent photosensitizers for efficient NIR‐II fluorescence imaging as well as photodynamic… read more here.
Keywords: fluorescence; fluorescence imaging; imaging guided; synergistic phototherapy ... See more keywords
Ultrasound‐Propelled Nanomotors Enable Activatable Near‐Infrared‐II Fluorescence Imaging‐Guided Synergistic Oxygen‐Independent and Oxygen‐Dependent Sonodynamic Therapy of Atherosclerosis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202503885
Abstract: Sonodynamic therapy (SDT) holds great promise as a therapeutic approach for treating atherosclerotic plaque. However, the therapeutic efficacy of SDT is hindered by the restricted tissue penetration depth and insufficient generation of reactive oxygen species… read more here.
Keywords: imaging guided; oxygen; fluorescence; sonodynamic therapy ... See more keywords
A Quenched Annexin V‐Fluorophore for the Real‐Time Fluorescence Imaging of Apoptotic Processes In Vitro and In Vivo
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DOI: 10.1002/advs.202002988
Abstract: Abstract Annexin‐based probes have long been used to study apoptotic cell death, which is of key importance to many areas of biological research, drug discovery, and clinical applications. Although apoptosis is a dynamic biological event… read more here.
Keywords: real time; apoptosis; fluorescence imaging; annexin ... See more keywords
NIR‐II Fluorescence Imaging‐guided Photothermal Activated Pyroptosis For Precision Therapy Of Glioma
Sign Up to like & getrecommendations! Published in 2025 at "ChemBioChem"
DOI: 10.1002/cbic.202400804
Abstract: The resistance of cancer cells to apoptosis poses a significant challenge in cancer therapy, driving the exploration of alternative cell death pathways such as pyroptosis, known for its rapid and potent effects. While initial efforts… read more here.
Keywords: therapy; pyroptosis; nir fluorescence; fluorescence imaging ... See more keywords
Shedding light on imaging safety: Decoding the origin of photocytotoxicity in RhB‐assisted fluorescence imaging
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202400049
Abstract: Photocytotoxicity represents a significant limitation in the application of dye‐assisted fluorescence imaging (FI), often resulting in undesirable cellular damage or even cell death, thereby restricting their practical utility. The prevalence of Rhodamine B (RhB) in… read more here.
Keywords: photocytotoxicity; fluorescence imaging; assisted fluorescence; safety ... See more keywords
Safety and Usefulness of Fluorescence Imaging Using Methylene Blue as a Fluorophore in a Japanese Population with Hepatobiliary and Pancreatic Diseases: A Phase I Study.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of hepato-biliary-pancreatic sciences"
DOI: 10.1002/jhbp.1293
Abstract: BACKGROUND Methylene blue (MB) has been used to treat methemoglobinemia. Recently, a fluorescence imaging technique using MB as a fluorophore was used in several region but still not in hepatobiliary and pancreatic surgery; thus, information… read more here.
Keywords: imaging using; safety; methylene blue; fluorescence imaging ... See more keywords
A retrospective pilot study to examine the feasibility of real‐time navigation for laparoscopic liver resections in intrahepatic cholangiocarcinoma using fusion indocyanine green fluorescence imaging
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25940
Abstract: Recently, PINPOINT, a novel laparoscopic fusion indocyanine green fluorescence imaging (IGFI) system has become available for laparoscopic liver resection. This study aims to characterize fluorescence patterns of intrahepatic cholangiocarcinoma (ICC) using the negative counterstaining method… read more here.
Keywords: laparoscopic; indocyanine green; fusion indocyanine; fluorescence ... See more keywords
Real‐time tissue perfusion assessment using fluorescence imaging topography scanning system: A preclinical investigation
Sign Up to like & getrecommendations! Published in 2022 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23560
Abstract: We previously developed a real‐time fluorescence imaging topography scanning (RFITS) system for intraoperative multimodal imaging, image‐guided surgery, and dynamic surgical navigation. The RFITS can capture intraoperative fluorescence, color reflectance, and surface topography concurrently and offers… read more here.
Keywords: system; topography; fluorescence imaging; real time ... See more keywords
Application of Zwitterionic Polymer Hydrogels to Optical Tissue Clearing for 3D Fluorescence Imaging.
Sign Up to like & getrecommendations! Published in 2021 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100170
Abstract: Zwitterionic polymers have both anion and cation groups in the side chain and have been used in various biomedical applications because of the unique properties. In this study, zwitterionic polymer hydrogels are applied to optical… read more here.
Keywords: fluorescence imaging; polymer; tissue; polymer hydrogels ... See more keywords
Aggregation‐Induced Emission Near‐Infrared (NIR)‐II‐Conjugated Polymers Coupled With Nonconjugated Segments for NIR‐II Fluorescence Imaging–Guided NIR‐II Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular Chemistry and Physics"
DOI: 10.1002/macp.202400268
Abstract: The development of conjugated polymer–based water‐soluble nanoparticles for near‐infrared‐II (NIR‐II) fluorescence (FL; 1000–1700 nm)‐guided photothermal therapy holds promise in advancing cancer treatment. However, excessive nonradiative decay leads to almost complete quenching of conjugated polymers’ fluorescence. Therefore,… read more here.
Keywords: conjugated polymers; nir fluorescence; fluorescence; fluorescence imaging ... See more keywords