Targeted Hsp70 fluorescence molecular endoscopy detects dysplasia in Barrett’s esophagus
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-021-05582-y
Abstract: The incidence of esophageal adenocarcinoma (EAC) has been increasing for decades without significant improvements in treatment. Barrett’s esophagus (BE) is best established risk factor for EAC, but current surveillance with random biopsies cannot predict progression… read more here.
Keywords: barrett esophagus; endoscopy; fluorescence molecular; hsp70 tpp ... See more keywords
A permissible region strategy for fluorescence molecular tomography
Sign Up to like & getrecommendations! Published in 2019 at "Optical Review"
DOI: 10.1007/s10043-019-00520-8
Abstract: A large-scale fluorescence measurement captured by non-contact fluorescence molecular tomography imaging system is utilized to reconstruct the three-dimensional distribution of fluorescent probe in small animals. However, this makes the computational burden heavier and restricts the… read more here.
Keywords: fluorescence; molecular tomography; fluorescence molecular; permissible region ... See more keywords
Paradigms in Fluorescence Molecular Imaging: Maximizing Measurement of Biological Changes in Disease, Therapeutic Efficacy, and Toxicology/Safety
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-018-1273-0
Abstract: Fluorescence molecular imaging (MI) is an important concept in preclinical research that focuses on the visualization of cellular and biological function in a non-invasive fashion to better understand in vivo disease processes and treatment effects.… read more here.
Keywords: biological changes; biology; fluorescence molecular; molecular imaging ... See more keywords
Fluorescence Molecular Tomography Reconstruction of Small Targets Using Stacked Auto-Encoder Neural Networks
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Access"
DOI: 10.1109/access.2020.2975807
Abstract: As a noninvasive and quantitative method, fluorescence molecular tomography (FMT) has many potential applications in biomedical field. It has the power to resolve in three-dimension (3D), the molecular processes in small animal in-vivo in both… read more here.
Keywords: reconstruction; using stacked; reconstruction small; molecular tomography ... See more keywords
Reconstruction for Fluorescence Molecular Tomography via Adaptive Group Orthogonal Matching Pursuit
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2019.2963815
Abstract: Objective: Fluorescence molecular tomography (FMT) is a promising medical imaging technology aimed at the non-invasive, specific, and sensitive detection of the distribution of fluorophore. Conventional sparsity prior-based methods of FMT commonly face problems such as… read more here.
Keywords: reconstruction; molecular tomography; group; fluorescence molecular ... See more keywords
Laplacian manifold regularization method for fluorescence molecular tomography
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.22.4.045009
Abstract: Abstract. Sparse regularization methods have been widely used in fluorescence molecular tomography (FMT) for stable three-dimensional reconstruction. Generally, ℓ1-regularization-based methods allow for utilizing the sparsity nature of the target distribution. However, in addition to sparsity,… read more here.
Keywords: molecular tomography; method; regularization; manifold regularization ... See more keywords
Standardization and implementation of fluorescence molecular endoscopy in the clinic
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.27.7.074704
Abstract: Abstract. Significance: Near-infrared fluorescence molecular endoscopy (NIR-FME) is an innovative technique allowing for in vivo visualization of molecular processes in hollow organs. Despite its potential for clinical translation, NIR-FME still faces challenges, for example, the… read more here.
Keywords: standardization; molecular endoscopy; fluorescence molecular; nir fme ... See more keywords
System configuration optimization for mesoscopic fluorescence molecular tomography.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical optics express"
DOI: 10.1364/boe.10.005660
Abstract: Tissue engineering applications demand 3D, non-invasive, and longitudinal assessment of bioprinted constructs. Current emphasis is on developing tissue constructs mimicking in vivo conditions; however, these are increasingly challenging to image as they are typically a… read more here.
Keywords: system; fluorescence; mesoscopic fluorescence; molecular tomography ... See more keywords
Sparsity-promoting Bayesian approximation error method for compensating for the mismodeling of optical properties in fluorescence molecular tomography.
Sign Up to like & getrecommendations! Published in 2017 at "Optics letters"
DOI: 10.1364/ol.42.003024
Abstract: In fluorescence molecular tomography, the quality of image reconstruction of fluorophore distribution is heavily reduced by the mismodeling of inaccurately known tissue optical properties. We propose an efficient sparsity-promoting Bayesian approximation error (spBAE) method to… read more here.
Keywords: promoting bayesian; optical properties; molecular tomography; method ... See more keywords
High-fidelity mesoscopic fluorescence molecular tomography based on SSB-Net.
Sign Up to like & getrecommendations! Published in 2022 at "Optics letters"
DOI: 10.1364/ol.475949
Abstract: The imaging fidelity of mesoscopic fluorescence molecular tomography (MFMT) in reflective geometry suffers from spatial nonuniformity of measurement sensitivity and ill-posed reconstruction. In this study, we present a spatially adaptive split Bregman network (SSB-Net) to… read more here.
Keywords: fidelity; ssb net; fluorescence molecular; fidelity mesoscopic ... See more keywords
Costs and effects of intra-operative fluorescence molecular imaging – A model-based, early assessment
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0198137
Abstract: Introduction Successful breast conserving cancer surgeries come along with tumor free resection margins and account for cosmetic outcome. Positive margins increase the likelihood of tumor recurrence. Intra-operative fluorescence molecular imaging (IFMI) aims to focus surgery… read more here.
Keywords: positive margins; fluorescence molecular; molecular imaging; operative fluorescence ... See more keywords