Identifying New Ligands for JNK3 by Fluorescence Thermal Shift Assays and Native Mass Spectrometry
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DOI: 10.1021/acsomega.2c00340
Abstract: The c-Jun N-terminal kinases (JNKs) are evolutionary highly conserved serine/threonine kinases. Numerous findings suggest that JNK3 is involved in the pathogenesis of neurodegenerative diseases, so the inhibition of JNK3 may be a potential therapeutic intervention.… read more here.
Keywords: native mass; mass spectrometry; jnk3; thermal shift ... See more keywords