Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides cthGAMP
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DOI: 10.1002/cbic.202200005
Abstract: The cGAS‐STING pathway is known for its role in sensing cytosolic DNA introduced by a viral infection, bacterial invasion or tumorigenesis. Free DNA is recognized by the cyclic GMP‐AMP synthase (cGAS) catalyzing the production of… read more here.
Keywords: cyclic dinucleotides; dinucleotides cthgamp; chemical synthesis; fluorescent cyclic ... See more keywords