Single-Molecule Biosensing of Alkaline Phosphatase in Cells and Serum Based on Dephosphorylation-Triggered Catalytic Assembly and Disassembly of the Fluorescent DNA Chain.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00603
Abstract: Alkaline phosphatase (ALP) is a valuable biomarker and effective therapeutic target for the diagnosis and treatment of diverse human diseases, including bone disorder, cardiovascular disease, and cancers. The reported ALP assays often suffer from laborious… read more here.
Keywords: single molecule; fluorescent dna; detection; alkaline phosphatase ... See more keywords
A fluorescent DNA hydrogel aptasensor based on the self-assembling of rolling circle amplification products for sensitive detection of OTA.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b06021
Abstract: A sensitive fluorescent DNA hydrogel aptasensor based on the self-assembling of rolling circle amplification (RCA) products was developed for Ochratoxin A (OTA) detection in beer. A competitive binding mode of aptamer, complementary sequence and target… read more here.
Keywords: dna hydrogel; fluorescent dna; hydrogel; hydrogel aptasensor ... See more keywords
Measuring DNA hybridization using fluorescent DNA-stabilized silver clusters to investigate mismatch effects on therapeutic oligonucleotides
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-018-0361-2
Abstract: BackgroundShort nucleic acid oligomers have found a wide range of applications in experimental physics, biology and medicine, and show potential for the treatment of acquired and genetic diseases. These applications rely heavily on the predictability… read more here.
Keywords: fluorescent dna; dna; hybridization; therapeutic oligonucleotides ... See more keywords