Development of a Highly Specific, Selective, and Sensitive Fluorescent Probe for Detection of Mycobacteria in Human Tissues
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102640
Abstract: Tuberculosis (TB), including extrapulmonary TB, is responsible for more than one million deaths in a year worldwide. Existing methods of mycobacteria detection have poor sensitivity, selectivity, and specificity, especially in human tissues. Herein, the synthesis… read more here.
Keywords: probe detect; detect mycobacteria; detection; fluorescent probe ... See more keywords
Specific spleen-accumulated NIR-II fluorescent probe for imaging-guided splenic operation.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300434
Abstract: Spleen is a large immune organ in body. Splenic operations such as splenectomy and intrasplenic injection are of paramount importance for immunological research and splenic diseases. Fluorescence imaging can vastly simplify these operations, but a… read more here.
Keywords: spleen accumulated; specific spleen; fluorescent probe; guided splenic ... See more keywords
Fluorescent Probe DCVJ Shows High Sensitivity for Characterization of Amyloid β‐Peptide Early in the Lag Phase
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700387
Abstract: The aggregation of intrinsically disordered and misfolded proteins in the form of oligomers and fibrils plays a crucial role in a number of neurological and neurodegenerative diseases. Currently, most probes and biophysical techniques that detect… read more here.
Keywords: fluorescent probe; shows high; dcvj shows; sensitivity ... See more keywords
Specific Detection of Extended‐Spectrum β‐Lactamase Activities with a Ratiometric Fluorescent Probe
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700447
Abstract: The dissemination of antimicrobial resistance around the world is one of the biggest threats to global public health. The acquisition and expression of extended‐spectrum β‐lactamases (ESBLs) in pathogenic bacterial are mainly responsible for bacterial resistance… read more here.
Keywords: fluorescent probe; detection; probe; ratiometric fluorescent ... See more keywords
Lessons in Organic Fluorescent Probe Discovery
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100171
Abstract: Fluorescent probes have gained profound use in biotechnology, drug discovery, medical diagnostics, molecular and cell biology. The development of methods for the translation of fluorophores into fluorescent probes continues to be a robust field for… read more here.
Keywords: discovery; probe discovery; fluorescent probe; lessons organic ... See more keywords
High‐Throughput Screening of Signal Peptide Library with Novel Fluorescent Probe
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202100523
Abstract: Nitrile hydratase (NHase) is an excellent biocatalyst for the synthesis of amide compounds and is composed of two heterologous subunits. However, the secretory expression of NHase has been difficult to achieve because of its complex… read more here.
Keywords: peptide library; fluorescent probe; throughput screening; high throughput ... See more keywords
Hypoxia Activated Fluorescent Probe Based on Self-immolative Block Copolymer.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100417
Abstract: This work reported a hypoxia activated fluorescent probe for tumor imaging by using self-immolative block copolymer with azobenzene linkage. The water-soluble polymer composed of self-immolative building blocks showed no obvious fluorescence. Under the hypoxic microenvironment… read more here.
Keywords: activated fluorescent; block copolymer; immolative block; fluorescent probe ... See more keywords
An ESIPT‐Based Ratiometric Fluorescent Probe for Highly Sensitive and Rapid Detection of Sulfite in Living Cells
Sign Up to like & getrecommendations! Published in 2019 at "ChemistryOpen"
DOI: 10.1002/open.201900242
Abstract: Abstract The novel ratiometric fluorescent probe HPQRB with an ESIPT effect based on Michael addition for highly sensitive and fast detection of sulfite in living HepG2 cells is reported. HPQRB can be easily synthesized by… read more here.
Keywords: fluorescent probe; detection; sulfite living; detection sulfite ... See more keywords
Chameleon-Like Fluorescent Probe for Monitoring Interplays between Three Organelles and Reporting Cell Damage Processes through Dramatic Color Change.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205026
Abstract: The in-depth study of the interplay and cooperation between multiple organelles is an important biological task. Single fluorescent probes for separate visualization of multiple organelles is a desirable molecular tool, but the construction of such… read more here.
Keywords: three organelles; cell; damage; fluorescent probe ... See more keywords
In vivo tumor imaging by a γ-glutamyl transpeptidase-activatable near-infrared fluorescent probe
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1181-9
Abstract: Abstractγ-Glutamyl transpeptidase (GGT), overexpressed in various cancer cells, has been perceived as a latent tumor biomarker. Thus, developing near-infrared (NIR) fluorescent GGT probes is highly desired for in vivo tumor imaging and studies. To our… read more here.
Keywords: fluorescent probe; probe; near infrared; glutamyl transpeptidase ... See more keywords
A tridecaptin-based fluorescent probe for differential staining of Gram-negative bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1465-0
Abstract: The traditional Gram-staining method, which was invented more than a century ago for differentiating bacteria as Gram positive or Gram negative, is still widely practiced in microbiology. However, Gram staining suffers from several problems which… read more here.
Keywords: fluorescent probe; staining gram; probe; gram negative ... See more keywords