Pi‐Class Glutathione S‐transferase (GSTP1)‐Selective Fluorescent Probes for Multicolour Imaging with Various Cancer‐Associated Enzymes
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200443
Abstract: Pi‐class glutathione S‐transferase (GSTP1) is highly expressed in a wide variety of human cancer tissues compared to the corresponding normal counterpart. Therefore, GSTP1 is a potential target enzyme for overcoming resistance to chemotherapeutic agents or… read more here.
Keywords: cancer; cancer associated; class glutathione; fluorescent probes ... See more keywords
The Evaluation of Ester Functionalised TCF‐Based Fluorescent Probes for the Detection of Bacterial Species
Sign Up to like & getrecommendations! Published in 2021 at "Israel Journal of Chemistry"
DOI: 10.1002/ijch.202000105
Abstract: The ester functionality is commonly seen in the areas of chemical biology and medicinal chemistry for the design of cell-permeable active molecules. Ester-based prodrug/pro-sensor strategies are employed to mask polar functional groups (i. e. carboxylic… read more here.
Keywords: tcf based; based fluorescent; fluorescent probes; tcf ... See more keywords
Fluorescent probes for nanoscopy: four categories and multiple possibilities.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600042
Abstract: Nanoscopy enables breaking down the light diffraction limit and reveals the nanostructures of objects being studied using light. In 2014, three scientists pioneered the development of nanoscopy and won the Nobel Prize in Chemistry. This… read more here.
Keywords: multiple possibilities; categories multiple; probes nanoscopy; four categories ... See more keywords
Rapid and Sensitive Detection of Cancer Cells with Activatable Fluorescent Probes for Enzyme Activity.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1258-3_17
Abstract: Fluorescence (FL)-guided detection of cancer is one of the most promising approaches to achieve intraoperative assessment of surgical margins. Enzymes, such as aminopeptidase, carboxypeptidase, and glycosidase, whose activities are increased in cancer, have attracted great… read more here.
Keywords: activatable fluorescent; rapid sensitive; cancer cells; cancer ... See more keywords
Chemoselective Acylation of Hydrazinopeptides to Access Fluorescent Probes for Time-Resolved FRET Assays on GPCRs.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9121-1_7
Abstract: Fluorescence techniques represent a powerful tool to investigate dynamic and functional architecture of GPCRs. Thus, fluorescent GPCR ligands have found various applications in cellular imaging, in the development of binding assays as replacements for radioligands… read more here.
Keywords: fluorescent; acylation hydrazinopeptides; time resolved; access fluorescent ... See more keywords
Two highly sensitive fluorescent probes based on cinnamaldehyde with large Stokes shift for sensing of HSO3− in pure water and living cells
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02827-x
Abstract: Two simple and novel fluorescent probes (CDC1 and CDC2) have been designed and prepared here for sensing HSO3− with large Stokes shifts (about 250 nm). The synthesized probes can react with HSO3− just in 2… read more here.
Keywords: fluorescent probes; cdc2; hso3 pure; pure water ... See more keywords
Fluorescent probes on the basis of coumarin derivatives for determining biogenic thiols and thiophenols
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02486-6
Abstract: In this minireview, we consider the reactivity of fluorescent probes on the basis of coumarin derivatives for the purpose of detecting biogenic thiols (cysteine, homocysteine, glutathione) and thiophenols. References are provided to literature sources from… read more here.
Keywords: probes basis; basis coumarin; coumarin derivatives; fluorescent probes ... See more keywords
Two novel fluorescent probes based on phenothiazine: synthesis and “naked-eye” colorimetric recognition of Hg2+
Sign Up to like & getrecommendations! Published in 2019 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-018-03715-x
Abstract: Two novel colorimetric and fluorescent probes 2-(1,3-dithiolanes)-10-ethyl phenothiazine (PHE–Ed) and 2-(1,3-dithianes)-10-ethyl phenothiazine (PHE–Pd) based on phenothiazine were successfully synthesized, and their structure was confirmed by NMR and high resolution mass spectra. Fluorescence investigations revealed that… read more here.
Keywords: hg2; novel fluorescent; based phenothiazine; two novel ... See more keywords
Biothiol-specific fluorescent probes with aggregation-induced emission characteristics
Sign Up to like & getrecommendations! Published in 2018 at "Science China Chemistry"
DOI: 10.1007/s11426-018-9300-5
Abstract: Biothiols are important species in physiological processes such as regulating protein structures, redox homeostasis and cell signalling. Alternation in the biothiol levels is associated with various pathological processes, therefore non-invasive fluorescent probes with high specificity… read more here.
Keywords: aggregation; aggregation induced; probes aggregation; biothiol specific ... See more keywords
Comparison of Free Zinc Levels Determined by Fluorescent Probes in THP1 Cells Using Microplate Reader and Flow Cytometer
Sign Up to like & getrecommendations! Published in 2020 at "Biological Trace Element Research"
DOI: 10.1007/s12011-020-02355-w
Abstract: Free zinc is involved in signal transduction within mammalian cells, acting as a second messenger. Gold standard for its analysis is currently the use of metal-responsive fluorescent probes. The present study elucidates the impact of… read more here.
Keywords: free zinc; zinc; flow cytometer; fluorescent probes ... See more keywords
A review of bioselenol-specific fluorescent probes: Synthesis, properties, and imaging applications.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.03.027
Abstract: Bioselenols are important substances for the maintenance of physiological balance and offer anticancer properties; however, their causal mechanisms and effectiveness have not been assessed. One way to explore their physiological functions is the in vivo detection… read more here.
Keywords: review bioselenol; specific fluorescent; fluorescent probes; bioselenol specific ... See more keywords